Simvastatin as a topical anti-inflammatory: Effect on airway epithelial cell homeostasis

被引:0
作者
Farrell, Nyssa Fox [1 ,5 ]
Pan, Jiehong [2 ]
Huang, Tao [2 ]
Piccirillo, Jay F. [3 ]
Goldstein, Bradley J. [4 ]
Brody, Steven L. [2 ]
机构
[1] Washington Univ, Dept Otolaryngol Head & Neck Surg, Div Rhinol, Sch Med, St Louis, MO USA
[2] Washington Univ, Dept Med, Div Pulm & Crit Care Med, Sch Med, St Louis, MO USA
[3] Washington Univ, Dept Otolaryngol Head & Neck Surg, Clin Outcomes Res Off, Sch Med, St Louis, MO USA
[4] Duke Univ, Dept Head & Neck Surg & Commun Sci, Sch Med, Durham, NC USA
[5] Washington Univ, Midcampus Ctr, St Louis Sch Med, Dept Otolaryngol Head & Neck Surg, 660 South Euclid Ave, St Louis, MO 63110 USA
关键词
medical therapy of chronic rhinosinusitis; therapeutics; topical therapy for chronic rhinosinusitis; NASAL;
D O I
10.1002/alr.23137
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
引用
收藏
页码:1817 / 1820
页数:4
相关论文
共 10 条
[1]   Repurposing of statins via inhalation to treat lung inflammatory conditions [J].
Bradbury, Peta ;
Traini, Daniela ;
Ammit, Alaina J. ;
Young, Paul M. ;
Ong, Hui Xin .
ADVANCED DRUG DELIVERY REVIEWS, 2018, 133 :93-106
[2]   ADVANTAGEOUS NASAL DRUG DELIVERY SYSTEM: A REVIEW [J].
Chhajed, Sachin ;
Sangale, Sagar ;
Barhate, S. D. .
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2011, 2 (06) :1322-1336
[3]   HUMAN NASAL AND BRONCHIAL EPITHELIAL-CELLS IN CULTURE - AN OVERVIEW OF THEIR CHARACTERISTICS AND FUNCTION [J].
DEVALIA, JL ;
DAVIES, RJ .
ALLERGY PROCEEDINGS, 1991, 12 (02) :71-79
[4]   Simvastatin Inhibits IL-5-Induced Chemotaxis and CCR3 Expression of HL-60-Derived and Human Primary Eosinophils [J].
Fu, Chia-Hsiang ;
Tsai, Wan-Chun ;
Lee, Ta-Jen ;
Huang, Chi-Che ;
Chang, Po-Hung ;
Pang, Jong-Hwei Su .
PLOS ONE, 2016, 11 (06)
[5]   Rho-Associated Protein Kinase Inhibition Enhances Airway Epithelial Basal-Cell Proliferation and Lentivirus Transduction [J].
Horani, Amjad ;
Nath, Aditya ;
Wasserman, Mollie G. ;
Huang, Tao ;
Brody, Steven L. .
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2013, 49 (03) :341-347
[6]   Nasal Epithelial Cells as Surrogates for Bronchial Epithelial Cells in Airway Inflammation Studies [J].
McDougall, Catherine M. ;
Blaylock, Morgan G. ;
Douglas, J. Graham ;
Brooker, Richard J. ;
Helms, Peter J. ;
Walsh, Garry M. .
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2008, 39 (05) :560-568
[7]   Quantifying Ciliary Dynamics during Assembly Reveals Stepwise Waveform Maturation in Airway Cells [J].
Oltean, Alina ;
Schaffer, Andrew J. ;
Bayly, Philip V. ;
Brody, Steven L. .
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2018, 59 (04) :511-522
[8]   Effect of simvastatin on transforming growth factor beta-1-induced myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts [J].
Park, Il-Ho ;
Park, Se-Jin ;
Cho, Jung-Sun ;
Moon, You-Mi ;
Moon, Jun-Hyeok ;
Kim, Tae Hoon ;
Lee, Sang Hag ;
Lee, Heung-Man .
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY, 2012, 26 (01) :7-11
[9]  
Ramezanpour M, 2017, RHINOLOGY, V55, P161, DOI [10.4193/Rhino16.284, 10.4193/Rhin16.284]
[10]   Effects of ophthalmologic solutions on sinonasal ciliated epithelium [J].
Workman, Alan D. ;
Carey, Ryan M. ;
Kohanski, Michael A. ;
Adappa, Nithin D. ;
Palmer, James N. ;
Cohen, Noam A. .
INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2017, 7 (08) :801-808