Radiological endpoints as surrogates for survival benefit in hepatocellular carcinoma trials: All that glitters is not gold

被引：17
作者：
Cabibbo, Giuseppe [1 ]
Bruix, Jordi [2 ]
机构：
[1] Univ Palermo, Dept Hlth Promot Mother & Child Care, Sect Gastroenterol & Hepatol, Internal Med & Med Specialties PROMISE, Piazza Clin 2, I-90127 Palermo, Italy
[2] Univ Barcelona, Hosp Clin Barcelona, Liver Unit, BCLC Grp,IDIBAPS,CIBEREHD, Villarroel 170, Barcelona 08036, Spain
来源：
JOURNAL OF HEPATOLOGY | 2023年 / 78卷 / 01期
关键词：
SORAFENIB; CANCER;
D O I：
10.1016/j.jhep.2022.10.018
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：8 / 11
页数：4
相关论文
共 22 条
[1]  
Abou-Alfa Ghassan K, 2022, NEJM Evid, V1, pEVIDoa2100070, DOI 10.1056/EVIDoa2100070
[2]   Endpoints in clinical trials for liver cancer and their value in evidence-based clinical decision making: An unresolved Gordian knot [J].
Bruix, Jordi .
JOURNAL OF HEPATOLOGY, 2021, 74 (06) :1483-1488
[3]   Insights into the success and failure of systemic therapy for hepatocellular carcinoma [J].
Bruix, Jordi ;
da Fonseca, Leonardo G. ;
Reig, Maria .
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 2019, 16 (10) :617-630
[4]   Assessment of treatment efficacy in hepatocellular carcinoma: Response rate, delay in progression or none of them [J].
Bruix, Jordi ;
Reig, Maria ;
Sangro, Bruno .
JOURNAL OF HEPATOLOGY, 2017, 66 (06) :1114-1117
[5]   Optimizing systemic therapy for advanced hepatocellular carcinoma: the key role of liver function [J].
Cabibbo, Giuseppe ;
Aghemo, Alessio ;
Lai, Quirino ;
Masarone, Mario ;
Montagnese, Sara ;
Ponziani, Francesca Romana .
DIGESTIVE AND LIVER DISEASE, 2022, 54 (04) :452-460
[6]   First-Line Immune Checkpoint Inhibitor-Based Sequential Therapies for Advanced Hepatocellular Carcinoma: Rationale for Future Trials [J].
Cabibbo, Giuseppe ;
Reig, Maria ;
Celsa, Ciro ;
Torres, Ferran ;
Battaglia, Salvatore ;
Enea, Marco ;
Rizzo, Giacomo Emanuele Maria ;
Petta, Salvatore ;
Calvaruso, Vincenza ;
Di Marco, Vito ;
Craxi, Antonio ;
Singal, Amit G. ;
Bruix, Jordi ;
Camma, Calogero .
LIVER CANCER, 2021, :75-84
[7]   Progression-Free Survival Early Assessment Is a Robust Surrogate Endpoint of Overall Survival in Immunotherapy Trials of Hepatocellular Carcinoma [J].
Cabibbo, Giuseppe ;
Celsa, Ciro ;
Enea, Marco ;
Battaglia, Salvatore ;
Rizzo, Giacomo Emanuele Maria ;
Busacca, Anita ;
Matranga, Domenica ;
Attanasio, Massimo ;
Reig, Maria ;
Craxi, Antonio ;
Camma, Calogero .
CANCERS, 2021, 13 (01) :1-14
[8]   Hepatic decompensation is the major driver of death in HCV-infected cirrhotic patients with successfully treated early hepatocellular carcinoma [J].
Cabibbo, Giuseppe ;
Petta, Salvatore ;
Barbara, Marco ;
Attardo, Simona ;
Bucci, Laura ;
Farinati, Fabio ;
Giannini, Edoardo G. ;
Negrini, Giulia ;
Ciccarese, Francesca ;
Rapaccini, Gian Lodovico ;
Di Marco, Maria ;
Caturelli, Eugenio ;
Zoli, Marco ;
Borzio, Franco ;
Sacco, Rodolfo ;
Virdone, Roberto ;
Marra, Fabio ;
Mega, Andrea ;
Morisco, Filomena ;
Benvegnu, Luisa ;
Gasbarrini, Antonio ;
Svegliati-Baroni, Gianluca ;
Foschi, Francesco Giuseppe ;
Olivani, Andrea ;
Masotto, Alberto ;
Nardone, Gerardo ;
Colecchia, Antonio ;
Persico, Marcello ;
Craxi, Antonio ;
Trevisani, Franco ;
Camma, Calogero .
JOURNAL OF HEPATOLOGY, 2017, 67 (01) :65-71
[9]   Sunitinib Versus Sorafenib in Advanced Hepatocellular Cancer: Results of a Randomized Phase III Trial [J].
Cheng, Ann-Lii ;
Kang, Yoon-Koo ;
Lin, Deng-Yn ;
Park, Joong-Won ;
Kudo, Masatoshi ;
Qin, Shukui ;
Chung, Hyun-Cheol ;
Song, Xiangqun ;
Xu, Jianming ;
Poggi, Guido ;
Omata, Masao ;
Lowenthal, Susan Pitman ;
Lanzalone, Silvana ;
Yang, Liqiang ;
Lechuga, Maria Jose ;
Raymond, Eric .
JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (32) :4067-+
[10]   A systematic review of meta-analyses assessing the validity of tumour response endpoints as surrogates for progression-free or overall survival in cancer [J].
Cooper, Katy ;
Tappenden, Paul ;
Cantrell, Anna ;
Ennis, Kate .
BRITISH JOURNAL OF CANCER, 2020, 123 (11) :1686-1696
123