GRADE pearls and pitfalls-Part 1: Systematic reviews and meta-analyses

被引:3
|
作者
Al Duhailib, Zainab [1 ,2 ,3 ]
Granholm, Anders [2 ,4 ]
Alhazzani, Waleed [2 ,5 ,6 ,7 ]
Oczkowski, Simon [2 ,6 ,7 ]
Belley-Cote, Emilie [2 ,6 ,7 ,8 ]
Moller, Morten Hylander [2 ,4 ,9 ]
机构
[1] King Faisal Specialist Hosp & Res Ctr, Dept Crit Care Med, Riyadh, Saudi Arabia
[2] Guidelines Intens Care Med Dev & Evaluat GUIDE Grp, Hamilton, ON, Canada
[3] Alfaisal Univ, Dept Med, Riyadh, Saudi Arabia
[4] Copenhagen Univ Hosp, Dept Intens Care, Rigshosp, Copenhagen, Denmark
[5] King Saud Univ, Coll Med, Dept Crit Care, Riyadh, Saudi Arabia
[6] McMaster Univ, Dept Med, Hamilton, ON, Canada
[7] McMaster Univ, Dept Hlth Res Methods Evidence & Impact, Hamilton, ON, Canada
[8] Publ Hlth Res Inst, Hamilton, ON, Canada
[9] Univ Copenhagen, Dept Clin Med, Copenhagen, Denmark
关键词
GRADE; meta-analyses; systematic reviews; CONTROLLED-TRIALS; QUALITY; GUIDELINES; STRENGTH; TOOL;
D O I
10.1111/aas.14386
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Background: The Grading of Recommendation, Assessment, Development and Evaluation (GRADE) approach is used to assess the certainty of evidence in systematic reviews and meta-analyses. Methods: We describe how the GRADE approach is used in systematic reviews and meta-analyses, including key points and examples. This overview is aimed at clinicians and researchers who are, or plan to be, involved in the development or assessment of systematic reviews with meta-analyses using GRADE. Results: We outline how the certainty of evidence is assessed, how the evidence is summarized using GRADE evidence profiles or summary of findings tables, how the results are communicated, and we discuss challenges, advantages, and disadvantages with using GRADE. Conclusions: This overview aims to provide an overview of how GRADE is used in systematic reviews and meta-analyses, and may be used by systematic review developers, methodologists, and evidence end-users.
引用
收藏
页码:584 / 592
页数:9
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