Microbiota Implications in Endocrine-Related Diseases: From Development to Novel Therapeutic Approaches

被引:17
作者
Clemente-Suarez, Vicente Javier [1 ,2 ]
Redondo-Florez, Laura [3 ]
Rubio-Zarapuz, Alejandro [1 ]
Martin-Rodriguez, Alexandra [1 ]
Tornero-Aguilera, Jose Francisco [1 ]
机构
[1] Univ Europea Madrid, Fac Sports Sci, Tajo St S-N, Madrid 28670, Spain
[2] Univ Costa, Grp Invest Cultura Educ & Soc, Barranquilla 080002, Colombia
[3] Univ Europea Madrid, Fac Biomed & Hlth Sci, Dept Hlth Sci, C Tajo S-N, Villaviciosa De Odon 28670, Spain
关键词
microbiota; endocrine-related cancers; hormones; endocrine pathology; dysbiosis; gut microbiome; endocrine disorders; CHAIN FATTY-ACIDS; GUT-BRAIN AXIS; AMERICAN THYROID ASSOCIATION; TYPE-1; DIABETES-MELLITUS; INTESTINAL MICROBIOTA; INSULIN SENSITIVITY; NONALCOHOLIC STEATOHEPATITIS; HEPATOCELLULAR-CARCINOMA; CESAREAN-SECTION; SEX-DIFFERENCES;
D O I
10.3390/biomedicines12010221
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This comprehensive review article delves into the critical role of the human microbiota in the development and management of endocrine-related diseases. We explore the complex interactions between the microbiota and the endocrine system, emphasizing the implications of microbiota dysbiosis for the onset and progression of various endocrine disorders. The review aims to synthesize current knowledge, highlighting recent advancements and the potential of novel therapeutic approaches targeting microbiota-endocrine interactions. Key topics include the impact of microbiota on hormone regulation, its role in endocrine pathologies, and the promising avenues of microbiota modulation through diet, probiotics, prebiotics, and fecal microbiota transplantation. We underscore the importance of this research in advancing personalized medicine, offering insights for more tailored and effective treatments for endocrine-related diseases.
引用
收藏
页数:37
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