Diet as an epigenetic factor in inflammatory bowel disease

被引：5
作者：
Marangoni, Karina [1 ,2 ]
Dorneles, Gilson [3 ]
da Silva, Daniella Miranda [4 ,5 ]
Pinto, Leticia Pereira [6 ]
Rossoni, Carina [7 ,8 ,9 ]
Fernandes, Sabrina Alves [6 ,10 ]
机构：
[1] Egas Moniz Sch Hlth & Sci, P-2820062 Caparica, Portugal
[2] Univ Fed Uberlandia, Natl Inst Sci & Technol Theranost & Nanobiotechnol, BR-38400902 Uberlandia, MG, Brazil
[3] Hosp Moinhos De Vento, Corp Social Responsibil, BR-90035004 Porto Alegre, Brazil
[4] Univ Fed Rio Grande Do Sul, Postgrad Program Gastroenterol, BR-91540000 Porto Alegre, Brazil
[5] Uniasselvi Grp Vitru, Dept Nutr, BR-89082262 Florianopolis, SC, Brazil
[6] Univ Fed Ciencias Saude Porto Alegre, Postgrad Program Hepatol, BR-90050170 Porto Alegre, Brazil
[7] Univ Lisbon, Inst Environm Hlth, Fac Med, P-1649026 Lisbon, Portugal
[8] Polytech Inst Beja, Phys Act & Hlth, P-7800000 Beja, Portugal
[9] Lusofona Univ, Nutr Sci, P-1749024 Lisbon, Portugal
[10] Univ Fed Ciencias Saude Porto Alegre, Postgrad Program Hepatol, Sarmento Leite 245, BR-90050170 Porto Alegre, Brazil
来源：
WORLD JOURNAL OF GASTROENTEROLOGY | 2023年 / 29卷 / 41期
关键词：
Inflammatory bowel disease; Epigenetics; Nutrition; Nutrigenetics; ONE-CARBON METABOLISM; VITAMIN-D DEFICIENCY; PATHOGENESIS; MICRORNAS; THERAPY; TARGETS; ACID;
D O I：
10.3748/wjg.v29.i41.5618
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Inflammatory bowel disease (IBD) has as a main characteristic the exacerbation of the immune system against enterocytes, compromising the individual's intestinal microbiota. This inflammatory cascade causes several nutritional deficiencies, which further compromise immunological functioning and, as a result, worsen the prognosis. This vicious cycle can be interrupted as the patient's dietary pattern meets their needs according to their clinical condition, acting directly on the inflammatory process of IBD through the interaction of food, intestinal microbiota, and epigenome. Specific nutritional intervention for IBD has a crucial role in preventing and managing disease activity. This review addresses epigenetic modifications through dietary compounds as a mechanism for modulating the intestinal microbiota of patients with IBD.
引用
收藏
页码：5618 / 5629
页数：12
相关论文
共 85 条
  • [1] The Role of Vitamins in Non-Alcoholic Fatty Liver Disease: A Systematic Review
    Abe, Rose Anne M.
    Masroor, Anum
    Khorochkov, Arseni
    Prieto, Jose
    Singh, Karan B.
    Nnadozie, Maduka C.
    Abdal, Muhammad
    Shrestha, Niki
    Mohammed, Lubna
    [J]. CUREUS JOURNAL OF MEDICAL SCIENCE, 2021, 13 (08)
  • [2] Diet, Gut Microbiome and Epigenetics: Emerging Links with Inflammatory Bowel Diseases and Prospects for Management and Prevention
    Aleksandrova, Krasimira
    Romero-Mosquera, Beatriz
    Hernandez, Vicent
    [J]. NUTRIENTS, 2017, 9 (09): : 1 - 13
  • [3] The molecular hallmarks of epigenetic control
    Allis, C. David
    Jenuwein, Thomas
    [J]. NATURE REVIEWS GENETICS, 2016, 17 (08) : 487 - 500
  • [4] Resveratrol Downregulates miR-31 to Promote T Regulatory Cells during Prevention of TNBS-Induced Colitis
    Alrafas, Haider Rasheed
    Busbee, Philip B.
    Nagarkatti, Mitzi
    Nagarkatti, Prakash S.
    [J]. MOLECULAR NUTRITION & FOOD RESEARCH, 2020, 64 (01)
  • [5] Nutrition and epigenetics: an interplay of dietary methyl donors, one-carbon metabolism and DNA methylation
    Anderson, Olivia S.
    Sant, Karilyn E.
    Dolinoy, Dana C.
    [J]. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2012, 23 (08) : 853 - 859
  • [6] Rethinking healthy eating in light of the gut microbiome
    Armet, Anissa M.
    Deehan, Edward C.
    O'Sullivan, Aidan F.
    Mota, Joao F.
    Field, Catherine J.
    Prado, Carla M.
    Lucey, Alice J.
    Walter, Jens
    [J]. CELL HOST & MICROBE, 2022, 30 (06) : 764 - 785
  • [7] Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
    Arpaia, Nicholas
    Campbell, Clarissa
    Fan, Xiying
    Dikiy, Stanislav
    van der Veeken, Joris
    deRoos, Paul
    Liu, Hui
    Cross, Justin R.
    Pfeffer, Klaus
    Coffer, Paul J.
    Rudensky, Alexander Y.
    [J]. NATURE, 2013, 504 (7480) : 451 - +
  • [8] Vitamin D Deficiency Promotes Epithelial Barrier Dysfunction and Intestinal Inflammation
    Assa, Amit
    Vong, Linda
    Pinnell, Lee J.
    Avitzur, Naama
    Johnson-Henry, Kathene C.
    Sherman, Philip M.
    [J]. JOURNAL OF INFECTIOUS DISEASES, 2014, 210 (08) : 1296 - 1305
  • [9] Genetic and epigenetic factors influencing vitamin D status
    Bahrami, Afsane
    Sadeghnia, Hamid Reza
    Tabatabaeizadeh, Seyed-Amir
    Bahrami-Taghanaki, Hamidreza
    Behboodi, Negin
    Esmaeili, Habibollah
    Ferns, Gordon A.
    Mobarhan, Majid Ghayour
    Avan, Amir
    [J]. JOURNAL OF CELLULAR PHYSIOLOGY, 2018, 233 (05) : 4033 - 4043
  • [10] Nutritional Aspects in Inflammatory Bowel Diseases
    Balestrieri, Paola
    Ribolsi, Mentore
    Guarino, Michele Pier Luca
    Emerenziani, Sara
    Altomare, Annamaria
    Cicala, Michele
    [J]. NUTRIENTS, 2020, 12 (02)
123456789