Milk exosomes: an oral drug delivery system with great application potential

被引：2
作者：
Tian, Meng-Yuan [1 ,2 ,3 ]
Hao, Dong-Xia [1 ,2 ,3 ]
Liu, Yang [1 ,2 ,3 ]
He, Jin [1 ,2 ,3 ]
Zhao, Zhuo-Hua [1 ,2 ,3 ]
Guo, Ting-Yu [4 ]
Li, Xing [1 ,2 ,3 ]
Zhang, Yuan [1 ,2 ,3 ]
机构：
[1] Shaanxi Normal Univ, Key Lab Med Resources & Nat Pharmaceut Chem, Minist Educ, Xian, Peoples R China
[2] Natl Engn Lab Resource Dev Endangered Crude Drugs, Xian, Peoples R China
[3] Shaanxi Normal Univ, Coll Life Sci, Xian, Peoples R China
[4] Shaanxi Normal Univ, Int Dept, High Sch, Xian, Peoples R China
来源：
FOOD & FUNCTION | 2023年 / 14卷 / 03期
关键词：
MESENCHYMAL STEM-CELLS; TARGETED-DELIVERY; SURFACE MODIFICATION; MESSENGER-RNA; COW MILK; IN-VITRO; BOVINE; MICRORNA; FORMULATION; TRANSPORT;
D O I：
10.1039/d2fo02013k
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Exosomes are extracellular vesicles with the smallest diameter, usually divided into cellular sources and body fluid sources. Due to their special properties different from cell-derived exosomes, the application of milk exosomes as an oral drug delivery system has increased greatly. This article introduces the physical and chemical properties of exosomes, separation technology, dyeing and labeling technology, targeted modification technology, and the application of milk exosomes in drug loading and disease therapies.
引用
收藏
页码：1320 / 1337
页数：18
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