Altered SOD1 maturation and post-translational modification in familial and sporadic ALS spinal cord motor neurons

被引：0
|
作者：
Trist, Benjamin [1 ,2 ]
Genoud, Sian [1 ,2 ]
Roudeau, Stephane [3 ,4 ]
Rookyard, Alexander [5 ]
Abdeen, Amr [1 ,2 ]
Cottam, Veronica [1 ,2 ]
White, Melanie [5 ]
Altvater, Jens [6 ]
Carmona, Asuncion [3 ,4 ]
Cordwell, Stuart [5 ]
Ortega, Richard [3 ,4 ]
Double, Kay [1 ,2 ]
机构：
[1] Univ Sydney, Brain & Mind Ctr, Sydney, Australia
[2] Univ Sydney, Sch Med Sci Neurosci, Sydney, Australia
[3] Univ Bordeaux, CENBG, Gradignan, France
[4] CNRS, Gradignan, France
[5] Univ Sydney, Sch Life & Environm Sci, Fac Sci, Sydney, Australia
[6] Univ Sydney, Sydney Mass Spectrometry, Sydney, Australia
来源：
JOURNAL OF NEUROCHEMISTRY | 2023年 / 166卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
B 10-34
引用
收藏
页码：140 / 141
页数：2
相关论文
共 50 条
  • [31] Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria
    Liu, J
    Lillo, C
    Jonsson, PA
    Velde, CV
    Ward, CM
    Miller, TM
    Subramaniam, JR
    Rothstein, JD
    Marklund, S
    Andersen, PM
    Brännström, T
    Gredal, O
    Wong, PC
    Williams, DS
    Cleveland, DW
    NEURON, 2004, 43 (01) : 5 - 17
  • [32] Post-Translational Modification Analysis of VDAC1 in ALS-SOD1 Model Cells Reveals Specific Asparagine and Glutamine Deamidation
    Pittala, Maria Gaetana Giovanna
    Reina, Simona
    Cubisino, Salvatore Antonio Maria
    Cucina, Annamaria
    Formicola, Beatrice
    Cunsolo, Vincenzo
    Foti, Salvatore
    Saletti, Rosaria
    Messina, Angela
    ANTIOXIDANTS, 2020, 9 (12) : 1 - 22
  • [33] Transplantation of NT neurons into the spinal cord of SOD1 mice causes dose-independent delay of motor deficits.
    Garbuzova-Davis, S
    Willing, AE
    Saporta, S
    Dellis, JT
    Haywood, AN
    Austin, LH
    Offutt, J
    Cahill, DW
    Sanberg, PR
    EXPERIMENTAL NEUROLOGY, 2002, 175 (02) : 442 - 442
  • [34] Overexpression of SOD1 protects vulnerable motor neurons after spinal cord injury by attenuating mitochondrial cytochrome c release
    Sugawara, T
    Lewén, A
    Gasche, Y
    Yu, FS
    Chan, PH
    FASEB JOURNAL, 2002, 16 (12): : 1997 - +
  • [35] Robust SOD1 knockdown in large mammal spinal cord using a novel delivery paradigm with AAV gene therapy targeting SOD1 for the treatment of SOD1-ALS
    Patzke, H.
    Chen, Q.
    Carroll, J.
    Wang, R.
    Zhou, P.
    Huang, C.
    Wang, X.
    Aubin, J.
    Nonnenmacher, M.
    Ren, X.
    Wang, W.
    Christensen, E.
    Johnson, B.
    Liu, L.
    Nguyen, T.
    Zhou, R.
    Hossbach, M.
    Deckert, J.
    Chen, F.
    Thompson, J.
    Federici, T.
    Boulis, N. M.
    Hou, J.
    Sah, D.
    HUMAN GENE THERAPY, 2018, 29 (12) : A81 - A82
  • [36] Cytoplasmic Restriction of Mutated SOD1 Impairs the DNA Repair Process in Spinal Cord Neurons
    Li, Jiaojie
    Song, Miyoung
    Moh, Sanghyun
    Kim, Heemin
    Kim, Dae-Hwan
    CELLS, 2019, 8 (12)
  • [37] ALS-Linked SOD1 Mutants Enhance Neurite Outgrowth and Branching in Adult Motor Neurons
    Osking, Zachary
    Ayers, Jacob I.
    Hildebrandt, Ryan
    Skruber, Kristen
    Brown, Hilda
    Ryu, Daniel
    Eukovich, Amanda R.
    Golde, Todd E.
    Borchelt, David R.
    Read, Tracy-Ann
    Vitriol, Eric A.
    ISCIENCE, 2019, 11 : 294 - +
  • [38] DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations
    Kim, Byung Woo
    Jeong, Ye Eun
    Wong, Margaret
    Martin, Lee J.
    ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2020, 8 (01)
  • [39] DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations
    Byung Woo Kim
    Ye Eun Jeong
    Margaret Wong
    Lee J. Martin
    Acta Neuropathologica Communications, 8
  • [40] Degeneration of respiratory motor neurons in the SOD1 G93A transgenic rat model of ALS
    Lladó, J
    Haenggeli, C
    Pardo, A
    Wong, V
    Benson, L
    Coccia, C
    Rothstein, JD
    Shefner, JM
    Maragakis, NJ
    NEUROBIOLOGY OF DISEASE, 2006, 21 (01) : 110 - 118
12345