Scleritis and Episcleritis following Coronavirus Disease (COVID-19) Vaccination

被引:5
作者
Sanjay, Srinivasan [1 ,4 ]
Handa, Ashit [1 ,2 ]
Kawali, Ankush [1 ]
Shetty, Rohit [3 ]
Bhakti Mishra, Sai [1 ]
Mahendradas, Padmamalini [1 ]
机构
[1] Narayana Nethralaya, Dept Uveitis & Ocular Immunol, Bangalore, India
[2] Narayana Nethralaya, Dept Retina, Bangalore, India
[3] Narayana Nethralaya, Dept Neuroophthalmol Cornea & Refract Surg, Bangalore, India
[4] Narayana Nethralaya, 121-C Chord Rd,Rajajinagar 1st R Block, Bengaluru 560010, India
关键词
COVID-19; vaccines; scleritis; episcleritis; COVISHIELD (TM); COVAXIN (TM); topical steroids; ACUTE MACULAR NEURORETINOPATHY; CLINICAL-FEATURES; AUTOIMMUNITY; INFECTION; UVEITIS;
D O I
10.1080/09273948.2023.2182324
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Introduction: Coronavirus disease (COVID-19) vaccines have been reported to have ocular side effects including scleritis and episcleritis.PurposeTo report scleritis and episcleritis within a month following administration of COVID-19 vaccine. Methods: Retrospective case series. Results: 15 eyes of 12 consecutive patients with scleritis and episcleritis from March 2021 to September 2021 were included. The mean time of onset of symptoms in patients with scleritis was 15.7 days (range, 4-30) and for episcleritis it was 13.2 days (range 2-30). Patients received COVISHIELD (TM) (10 patients) and COVAXIN (TM) (2 patients). Five patients had denovo inflammation and seven had recurrent inflammation. Episcleritis patients were treated with topical steroids and systemic COX2 inhibitors while patients with scleritis were treated with topical steroids/oral steroids/antiviral medications depending on the aetiology. Conclusion: Scleritis and episcleritis following COVID-19 vaccination are milder and do not require intensive immunosuppression except in rare cases.
引用
收藏
页码:1184 / 1190
页数:7
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[1]   Drug-induced uveitis: A review [J].
Agarwal, Manisha ;
Majumder, Parthopratim Dutta ;
Babu, Kalpana ;
Konana, VinayaKumar ;
Goyal, Mallika ;
Touhami, Sara ;
Stanescu-Segall, Dinu ;
Bodaghi, Bahram .
INDIAN JOURNAL OF OPHTHALMOLOGY, 2020, 68 (09) :1799-1807
[2]  
[Anonymous], EYEWIKIAAO
[3]  
[Anonymous], 2014, WHO, World Health Organization
[4]  
[Anonymous], India-COVID19 Vaccine Tracker
[5]  
[Anonymous], FAQS COVID 19 VACCIN
[6]  
[Anonymous], Press Statement by the Drugs Controller General of India (DCGI) on Restricted Emergency approval of COVID-19 virus vaccine
[7]  
[Anonymous], SERUM I INDIA CHADOX
[8]   In the eye of the storm: SARS-CoV-2 infection and replication at the ocular surface? [J].
Armstrong, Lyle ;
Collin, Joseph ;
Mostafa, Islam ;
Queen, Rachel ;
Figueiredo, Francisco C. ;
Lako, Majlinda .
STEM CELLS TRANSLATIONAL MEDICINE, 2021, 10 (07) :976-986
[9]   Uveitis and Other Ocular Complications Following COVID-19 Vaccination [J].
Bolletta, Elena ;
Iannetta, Danilo ;
Mastrofilippo, Valentina ;
De Simone, Luca ;
Gozzi, Fabrizio ;
Croci, Stefania ;
Bonacini, Martina ;
Belloni, Lucia ;
Zerbini, Alessandro ;
Adani, Chantal ;
Fontana, Luigi ;
Salvarani, Carlo ;
Cimino, Luca .
JOURNAL OF CLINICAL MEDICINE, 2021, 10 (24)
[10]  
COVAXIN, 2024, India's first indigenous Covid-19 vaccine