Influence of the Mediterranean Diet on Healthy Aging

被引：52
作者：
Carmen Andreo-Lopez, Maria [1 ]
Contreras-Bolivar, Victoria [1 ,2 ]
Munoz-Torres, Manuel [1 ,2 ,3 ,4 ]
Garcia-Fontana, Beatriz [2 ,3 ,5 ]
Garcia-Fontana, Cristina [1 ,2 ,3 ]
机构：
[1] Univ Hosp Clin San Cecilio, Endocrinol & Nutr Unit, Granada 18016, Spain
[2] Inst Invest Biosanitaria Granada Ibs Granada, Granada 18014, Spain
[3] Inst Salud Carlos III, CIBER Frailty & Hlth Aging CIBERFES, Granada 18012, Spain
[4] Univ Granada, Dept Med, Granada 18016, Spain
[5] Univ Granada, Dept Cell Biol, Granada 18016, Spain
来源：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2023年 / 24卷 / 05期
关键词：
aging; Mediterranean diet; molecular pathways; microbiome; VIRGIN OLIVE-OIL; ENDOPLASMIC-RETICULUM STRESS; POLYUNSATURATED FATTY-ACIDS; INHIBITS TUMOR-GROWTH; CHAIN AMINO-ACIDS; OXIDATIVE STRESS; DNA-DAMAGE; TELOMERE LENGTH; MITOCHONDRIAL DYSFUNCTION; CARDIOVASCULAR-DISEASE;
D O I：
10.3390/ijms24054491
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The life expectancy of the global population has increased. Aging is a natural physiological process that poses major challenges in an increasingly long-lived and frail population. Several molecular mechanisms are involved in aging. Likewise, the gut microbiota, which is influenced by environmental factors such as diet, plays a crucial role in the modulation of these mechanisms. The Mediterranean diet, as well as the components present in it, offer some proof of this. Achieving healthy aging should be focused on the promotion of healthy lifestyle habits that reduce the development of pathologies that are associated with aging, in order to increase the quality of life of the aging population. In this review we analyze the influence of the Mediterranean diet on the molecular pathways and the microbiota associated with more favorable aging patterns, as well as its possible role as an anti-aging treatment.
引用
收藏
页数：35
相关论文
共 376 条
[1]   Natural antioxidants in the management of Parkinson's disease: Review of evidence from cell line and animal models [J].
Abdul-Latif, Reem ;
Stupans, Ieva ;
Allahham, Ayman ;
Adhikari, Benu ;
Thrimawithana, Thilini .
JOURNAL OF INTEGRATIVE MEDICINE-JIM, 2021, 19 (04) :300-310
[2]   Olive-Oil-Derived Oleocanthal Enhances β-Amyloid Clearance as a Potential Neuroprotective Mechanism against Alzheimer's Disease: In Vitro and in Vivo Studies [J].
Abuznait, Alaa H. ;
Qosa, Hisham ;
Busnena, Belnaser A. ;
El Sayed, Khalid A. ;
Kaddoumi, Amal .
ACS CHEMICAL NEUROSCIENCE, 2013, 4 (06) :973-982
[3]   Adherence to the Mediterranean Diet Has a Protective Role against Metabolic and DNA Damage Markers in Colorectal Cancer Patients [J].
Acevedo-Leon, Delia ;
Angel Gomez-Abril, Segundo ;
Monzo-Beltran, Lidia ;
Estan-Capell, Nuria ;
Arroyo-Montanes, Rafael ;
Banuls, Celia ;
Salas-Salvado, Jordi ;
Saez, Guillermo .
ANTIOXIDANTS, 2022, 11 (03)
[4]   Omega-3 polyunsaturated fatty acids improve mitochondrial dysfunction in brain aging - Impact of Bcl-2 and NPD-1 like metabolites [J].
Afshordel, Sarah ;
Hagl, Stephanie ;
Werner, Deborah ;
Roehner, Nelli ;
Koegel, Donat ;
Bazan, Nicolas G. ;
Eckert, Gunter P. .
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 2015, 92 :23-31
[5]   Low fruit consumption and folate deficiency are associated with LINE-1 hypomethylation in women of a cancer-free population [J].
Agodi, Antonella ;
Barchitta, Martina ;
Quattrocchi, Annalisa ;
Maugeri, Andrea ;
Canto, Carolina ;
Marchese, Anna Elisa ;
Vinciguerra, Manlio .
GENES AND NUTRITION, 2015, 10 (05)
[6]   Genome instability:: a mechanistic view of its causes and consequences [J].
Aguilera, Andres ;
Gomez-Gonzalez, Belen .
NATURE REVIEWS GENETICS, 2008, 9 (03) :204-217
[7]   A Recent Update on the Effects of Omega-3 Fatty Acids in Alzheimer's Disease [J].
Ajith, Thekkuttuparambil Ananthanarayanan .
CURRENT CLINICAL PHARMACOLOGY, 2018, 13 (04) :252-260
[8]   Hypoglycemic and antioxidant effect of oleuropein in alloxan-diabetic rabbits [J].
Al-Azzawie, HF ;
Alhamdani, MSS .
LIFE SCIENCES, 2006, 78 (12) :1371-1377
[9]   Weight Gain After Fecal Microbiota Transplantation [J].
Alang, Neha ;
Kelly, Colleen R. .
OPEN FORUM INFECTIOUS DISEASES, 2015, 2 (01)
[10]   Neuroprotective properties of resveratrol in different neurodegenerative disorders [J].
Albani, Diego ;
Polito, Letizia ;
Signorini, Alessandra ;
Forloni, Gianluigi .
BIOFACTORS, 2010, 36 (05) :370-376
12345678910