Sleep Disturbance in Systemic Sclerosis and the Associations Between Sleep and Pulmonary Hypertension: A Pilot Study

被引:1
|
作者
Turk, Ipek [1 ]
Arslan, Didem [1 ]
Kara, Kezban Aslan [2 ]
Gok, Duygu Kurt [2 ]
Cagliyan, caglar Emre [3 ]
Hanta, Ismail [4 ]
Unal, Ilker [5 ]
机构
[1] Cukurova Univ, Dept Internal Med, Div Rheumatol, Fac Med, Adana, Turkiye
[2] Cukurova Univ, Fac Med, Dept Neurol, Adana, Turkiye
[3] Cukurova Univ, Fac Med, Dept Cardiol, Adana, Turkiye
[4] Cukurova Univ, Fac Med, Dept Pulm Dis, Adana, Turkiye
[5] Cukurova Univ, Fac Med, Dept Biostat, Adana, Turkiye
来源
JOURNAL OF TURKISH SLEEP MEDICINE-TURK UYKU TIBBI DERGISI | 2024年 / 11卷 / 01期
关键词
Obstructive sleep apnea; systemic sclerosis; pulmonary hypertension; apnea-hypopnea index; APNEA; CLASSIFICATION; SYMPTOMS; CRITERIA;
D O I
10.4274/jtsm.galenos.2023.58661
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective: Major differences in sleep architecture are observed in patients with systemic sclerosis (SSc). The aim of this study was to investigate the sleep pattern and frequency of obstructive sleep apnea (OSA) in patients with SSc, and compare sleep patterns in patients with and without pulmonary hypertension (PH). Materials and Methods: Patients with SSc and symptoms of hypersomnia or insomnia who underwent polysomnography examinations were evaluated. The clinical data of patients were obtained from the patient files. The subjects were separated into two groups (PH-positive and PH-negative). OSA was defined as an apnea-hypopnea index (AHI) >= 5. Sleep parameters were evaluated between the groups. Results: Thirty-six patients with SSc (88.9% females; mean age: 53.1 +/- 11.2 years), 27 with diffuse SSc, and 9 with limited-type SSc were enrolled in the study. Approximately 30.6% of the patients with SSc had AHI >= 5 and 13.9% of patients had AHI >= 15. Eight patients with SSc (22.2%) had a periodic leg movement index (PMLI) above 5/h. The percentages of patients with AHI >= 5 and AHI >= 15 were 25.9% and 7.4% in the PH-negative group and 44.4% and 33.3% in the PH-positive group, respectively. The duration of the rapid eye movement sleep stage was significantly shorter in patients with SSc and PH than in those without PH (p=0.02). The percentages of patients with PMLI >5/h were 14.8% in the PH-negative group and 44.4% in the PH-positive group (p=0.086). Conclusion: Sleep disorders are more commonly observed in patients with SSc. Furthermore, OSA and PH are associated with SSc.
引用
收藏
页码:45 / 51
页数:7
相关论文
共 50 条
  • [1] Sleep quality and clinical association with sleep disturbance in systemic sclerosis
    Wongthawa, Nonthaphorn
    So-gnern, Apichart
    Mahakkanukrauh, Ajanee
    Suwannaroj, Siraphop
    Foocharoen, Chingching
    BMC RHEUMATOLOGY, 2023, 7 (01)
  • [2] Sleep quality and clinical association with sleep disturbance in systemic sclerosis
    Nonthaphorn Wongthawa
    Apichart So-gnern
    Ajanee Mahakkanukrauh
    Siraphop Suwannaroj
    Chingching Foocharoen
    BMC Rheumatology, 7
  • [3] Significance of serum uric acid in pulmonary hypertension due to systemic sclerosis: a pilot study
    Dimitroulas, Theodoros
    Giannakoulas, Georgios
    Dimitroula, Hariklia
    Sfetsios, Tilemahos
    Parcharidou, Despina
    Karvounis, Haralambos
    Settas, Loukas
    RHEUMATOLOGY INTERNATIONAL, 2011, 31 (02) : 263 - 267
  • [4] Significance of serum uric acid in pulmonary hypertension due to systemic sclerosis: a pilot study
    Theodoros Dimitroulas
    Georgios Giannakoulas
    Hariklia Dimitroula
    Tilemahos Sfetsios
    Despina Parcharidou
    Haralambos Karvounis
    Loukas Settas
    Rheumatology International, 2011, 31 : 263 - 267
  • [5] The relationship between pulmonary hypertension and obstructive sleep apnea
    Wong, Hang S.
    Williams, Adrian J.
    Mok, YingJuan
    CURRENT OPINION IN PULMONARY MEDICINE, 2017, 23 (06) : 517 - 521
  • [6] Pulmonary Hypertension in Systemic Sclerosis
    Chatterjee, Soumya
    SEMINARS IN ARTHRITIS AND RHEUMATISM, 2011, 41 (01) : 19 - 37
  • [7] Hypoxemia during sleep and overnight rostral fluid shift in pulmonary arterial hypertension: a pilot study
    Jutant, Etienne-Marie
    Montani, David
    Sattler, Caroline
    Guenther, Sven
    Sitbon, Olivier
    Garcia, Gilles
    Arnulf, Isabelle
    Humbert, Marc
    Similowski, Thomas
    Redolfi, Stefania
    PULMONARY CIRCULATION, 2021, 11 (02)
  • [8] A pilot study of dimethyl fumarate in pulmonary arterial hypertension associated with systemic sclerosis
    Kong, Kristi
    Koontz, Diane
    Morse, Christina
    Roth, Eileen
    Domsic, Robyn T.
    Simon, Marc A.
    Stratton, Eric
    Buchholz, Connor
    Tobin-Finch, Kimberly
    Simms, Robert
    George, M. Patricia
    Hassoun, Paul M.
    Farber, Harrison
    Lafyatis, Robert
    JOURNAL OF SCLERODERMA AND RELATED DISORDERS, 2021, 6 (03) : 242 - 246
  • [9] Prevalence and correlates of sleep disturbance in systemic sclerosis-results from the UCLA scleroderma quality of life study
    Frech, Tracy
    Hays, Ron D.
    Maranian, Paul
    Clements, Philip J.
    Furst, Daniel E.
    Khanna, Dinesh
    RHEUMATOLOGY, 2011, 50 (07) : 1280 - 1287