The Relationship Between Myocardial Infarction and Estrogen Use: A Literature Review

被引：5

作者：

Javed, Ayesha ^{[1
]}

Ravi, Phanish C. ^{[2
]}

Delvi, Sarah Bilal ^{[3
]}

Hussain, Iqra Faraz ^{[4
]}

Acosta, G. Arnaldo J. ^{[5
]}

Iqbal, Warda ^{[4
]}

Krishnamaneni, Vamsi ^{[6
]}

Alasaadi, Saya ^{[7
]}

Pradhan, Swetapadma ^{[8
]}

Vashisht, Rishabh ^{[9
]}

Modi, Shivani ^{[10
]}

机构：

[1] Hearts Int Hosp, Gynecol, Rawalpindi, Pakistan

[2] Sri Venkata Sai Med Coll, Med & Surg, Hyderabad, Telangana, India

[3] Vydehi Inst Med Sci & Res Ctr, Internal Med, Bangalore, India

[4] Karachi Med & Dent Coll, Gynecol, Karachi, Pakistan

[5] Alfredo Van Grieken Univ Hosp, Endocrinol, Coro, Venezuela

[6] Katuri Med Coll & Hosp, Internal Med, Guntur, India

[7] Univ Coll Dublin, Med, Dublin, Ireland

[8] European Univ, Med, Fac Med, Tbilisi, Georgia

[9] Non Resident Indian NRI Med Coll, Internal Med, Vijayawada, India

[10] Albert Einstein Healthcare Network, Internal Med, Philadelphia, PA 19141 USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 09期

关键词：

cvd; transdermal estrogen; estrone; estradiol; myocardial infarction; CORONARY-HEART-DISEASE; CARDIOVASCULAR-DISEASE; ORAL-CONTRACEPTIVES; HORMONE-THERAPY; PROGESTIN; OUTCOMES; EVENTS; RISK;

D O I：

10.7759/cureus.46134

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This thorough literature evaluation was prompted by significant research into the complex interactions between estrogen use and myocardial infarction (MI). Estrogen has fascinated researchers because of its possible cardioprotective benefits and its impact on cardiovascular health. In order to clarify the connection between estrogen use and the risk of MI, this review critically examines the body of prior evidence.This review focuses on estrogen and its pivotal role in cardiovascular health, concentrating on lipid metabolism, vasodilation, inflammation, and endothelial function. It examines contentious data about estrogen therapy's heart-protective effects, taking into account age, initiation timing, dosage, and dosage of administration. Genetic and epigenetic influences on MI risk among estrogen users highlight intricate, personalized estrogen effects.The conclusion summarizes the main findings and emphasizes the need for an all-encompassing strategy for initiating and managing estrogen medication. It is crucial to consider patient-specific traits and risk factors to successfully customize treatment regimens. This review sheds vital light on the potential directions for better cardiovascular treatment for postmenopausal women by shedding light on the complex link between estrogen use and myocardial infarction. The review also identifies research gaps and future objectives in this area, highlighting the demand for novel medicines and individualized strategies to improve cardiovascular outcomes.

引用

页数：7

共 31 条

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