The effects of SOY extract nutraceuticals on postmenopausal women's health: A randomized, double-blind, placebo-controlled trial

被引：2

作者：

Takuathung, Mingkwan Na ^{[1
,2
]}

Teekachunhatean, Supanimit ^{[1
,2
]}

Chansakaow, Sunee ^{[1
,2
,3
]}

Klinjan, Preeyaporn ^{[1
,2
]}

Inpan, Ratchanon ^{[1
,2
,4
]}

Kongta, Nattharinee ^{[1
]}

Tipduangta, Pratchaya ^{[3
]}

Tipduangta, Pramote ^{[5
]}

Dukaew, Nahathai ^{[1
,2
]}

Sakuludomkan, Chotiwit ^{[1
,2
]}

Koonrungsesomboon, Nut ^{[1
,2
]}

机构：

[1] Chiang Mai Univ, Fac Med, Dept Pharmacol, Chiang Mai 50200, Thailand

[2] Chiang Mai Univ, Fac Med, Clin Res Ctr Food & Herbal Prod Trials & Dev CR FA, Chiang Mai 50200, Thailand

[3] Chiang Mai Univ, Fac Pharm, Dept Pharmaceut Sci, Chiang Mai 50200, Thailand

[4] Chiang Mai Univ, Off Res Adm, Chiang Mai 50200, Thailand

[5] Chiang Mai Univ, Fac Pharm, Chiang Mai 50200, Thailand

来源：

JOURNAL OF FUNCTIONAL FOODS | 2024年 / 113卷

关键词：

Soy; Isoflavones; Skin; Bone; Cholesterol; Postmenopausal women; ORAL SUPPLEMENT; VITAMIN-C; MENOPAUSAL; SKIN; PHYTOESTROGENS; METAANALYSIS; ISOFLAVONES; IMPROVES; PROTEIN; ZINC;

D O I：

10.1016/j.jff.2024.106055

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Postmenopausal women experience physiological changes due to estrogen decline, affecting skin aging, bone health, and quality of life. The present study investigated the effects of the soy extract nutraceutical (SOY) product on facial skin health, bone turnover markers, menopausal symptoms, and quality of life in postmenopausal women by means of a randomized controlled trial. The effects of the product on lipids profiles, glucose levels, and insulin parameters were also explored. Participants received either the SOY product (n = 50) or a placebo (n = 50) for 12 weeks. The results showed significant improvements in facial skin wrinkle and bone turnover markers in the SOY group. While no major differences were observed in menopausal symptoms and quality of life between groups, the SOY group exhibited a significant reduction in total cholesterol levels. This study underscores the SOY product's potential in addressing facial skin aging, bone health, and cholesterol management in postmenopausal women.

引用

页数：9

共 48 条

[31] Vitamin C supplementation lowers serum low-density lipoprotein cholesterol and triglycerides: a meta-analysis of 13 randomized controlled trials [J].