Effects of probe parameters on radio-frequency ablation of localized liver cancer using a personalized patient treatment planning

This study investigates the role of different types of probes in Radiofrequency ablation based thermal therapy for tumours and surrounding healthy tissues. The findings demonstrate the significance of understanding the relationship between probe geometry, temperature distribution, and tissue response to optimize thermal therapies' design and application. By fine-tuning probe characteristics, such as radius, length, and power input, practitioners can tailor treatments for specific tissues, optimizing therapeutic outcomes while minimizing risks to healthy tissues. Additionally, the study sheds light on heat transfer mechanisms during thermal ablation, highlighting the importance of considering probe characteristics in treatment protocols. Results indicate that increasing power input leads to higher maximum temperatures, particularly in single-point probes, raising concerns about potential tissue damage at high-power settings. Furthermore, increasing the probe radius shows slight temperature reductions for both single-point and multi-point probes. Blood perfusion plays a significant role in regulating temperature, leading to temperature reductions in both probe types. This research emphasizes the importance of fine-tuning probe characteristics for improved thermal therapies and advances our understanding of thermal physics in biological systems, promising advancements in medical technology.