von-Hippel Lindau and Hypoxia-Inducible Factor at the Center of Renal Cell Carcinoma Biology

被引：4
作者：
Shirole, Nitin H. [1 ]
Kaelin Jr, William G. [1 ,2 ,3 ,4 ]
机构：
[1] Dana Farber Canc Inst, 450 Brookline Ave, Boston, MA 02215 USA
[2] Harvard Med Sch, Brigham & Womens Hosp, Boston, MA USA
[3] Howard Hughes Med Inst, Chevy Chase, MD USA
[4] Dana Farber Canc Inst, M457,450 Brookline Ave, Boston, MA 02215 USA
来源：
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2023年 / 37卷 / 05期
关键词：
Hypoxia-inducible factor; Kidney cancer; Renal cell carcinoma; von Hippel-Lindau disease; Belzutifan; TUMOR-SUPPRESSOR GENE; HEREDITARY MULTIPLE FIBROFOLLICULOMAS; BAP1 MUTATIONS PREDISPOSE; PAS-B DOMAIN; GERMLINE MUTATION; GROWTH-FACTOR; HIF-ALPHA; CYCLIN D1; FACTOR (HIF)-1-ALPHA; CABOZANTINIB XL184;
D O I：
10.1016/j.hoc.2023.04.011
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
[No abstract available]
引用
收藏
页码：809 / 825
页数：17
相关论文
共 142 条
  • [1] Multi-omics analysis reveals contextual tumor suppressive and oncogenic gene modules within the acute hypoxic response
    Andrysik, Zdenek
    Bender, Heather
    Galbraith, Matthew D.
    Espinosa, Joaquin M.
    [J]. NATURE COMMUNICATIONS, 2021, 12 (01)
  • [2] Loss of von Hippel-Lindau protein causes cell density dependent deregulation of CyclinD1 expression through Hypoxia-inducible factor
    Baba, M
    Hirai, S
    Yamada-Okabe, H
    Hamada, K
    Tabuchi, H
    Kobayashi, K
    Kondo, K
    Yoshida, M
    Yamashita, A
    Kishida, T
    Nakaigawa, N
    Nagashima, Y
    Kubota, Y
    Yao, M
    Ohno, S
    [J]. ONCOGENE, 2003, 22 (18) : 2728 - 2738
  • [3] Genetic and epigenetic analysis of von Hippel-Lindau (VHL) gene alterations and relationship with clinical variables in sporadic renal cancer
    Banks, RE
    Tirukonda, P
    Taylor, C
    Hornigold, N
    Astuti, D
    Cohen, D
    Maher, ER
    Stanley, AJ
    Harnden, P
    Joyce, A
    Knowles, M
    Selby, PJ
    [J]. CANCER RESEARCH, 2006, 66 (04) : 2000 - 2011
  • [4] A germline mutation in PBRM1 predisposes to renal cell carcinoma
    Benusiglio, Patrick R.
    Couve, Sophie
    Gilbert-Dussardier, Brigitte
    Deveaux, Sophie
    Le Jeune, Helene
    Da Costa, Melanie
    Fromont, Gaelle
    Memeteau, Francoise
    Yacoub, Mokrane
    Coupier, Isabelle
    Leroux, Dominique
    Mejean, Arnaud
    Escudier, Bernard
    Giraud, Sophie
    Gimenez-Roqueplo, Anne-Paule
    Blondel, Christophe
    Frouin, Eric
    Teh, Bin T.
    Ferlicot, Sophie
    Bressac-de Paillerets, Brigitte
    Richard, Stephane
    Gad, Sophie
    [J]. JOURNAL OF MEDICAL GENETICS, 2015, 52 (06) : 426 - 430
  • [5] Patterns of Gene Expression and Copy-Number Alterations in von-Hippel Lindau Disease-Associated and Sporadic Clear Cell Carcinoma of the Kidney
    Beroukhim, Rameen
    Brunet, Jean-Philippe
    Di Napoli, Arianna
    Mertz, Kirsten D.
    Seeley, Apryle
    Pires, Maira M.
    Linhart, David
    Worrell, Robert A.
    Moch, Holger
    Rubin, Mark A.
    Sellers, William R.
    Meyerson, Matthew
    Linehan, W. Marston
    Kaelin, William G., Jr.
    Signoretti, Sabina
    [J]. CANCER RESEARCH, 2009, 69 (11) : 4674 - 4681
  • [6] bHLH-PAS proteins in cancer
    Bersten, David C.
    Sullivan, Adrienne E.
    Peet, Daniel J.
    Whitelaw, Murray L.
    [J]. NATURE REVIEWS CANCER, 2013, 13 (12) : 827 - 841
  • [7] Bindra RS, 2002, CANCER RES, V62, P3014
  • [8] HEREDITARY MULTIPLE FIBROFOLLICULOMAS WITH TRICHODISCOMAS AND ACROCHORDONS
    BIRT, AR
    HOGG, GR
    DUBE, WJ
    [J]. ARCHIVES OF DERMATOLOGY, 1977, 113 (12) : 1674 - 1677
  • [9] The hypoxic response of tumors is dependent on their microenvironment
    Blouw, B
    Song, HQ
    Tihan, T
    Bosze, J
    Ferrara, N
    Gerber, HP
    Johnson, RS
    Bergers, G
    [J]. CANCER CELL, 2003, 4 (02) : 133 - 146
  • [10] Kinase requirements in human cells: III. Altered kinase requirements in VHL-/- cancer cells detected in a pilot synthetic lethal screen
    Bommi-Reddy, Archana
    Almeciga, Ingrid
    Sawyer, Jacqueline
    Geisen, Christoph
    Li, Wenliang
    Harlow, Ed
    Kaelin, William G., Jr.
    Grueneberg, Dorre A.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (43) : 16484 - 16489
12345678910