Conformable ultrasound breast patch for deep tissue scanning and imaging

被引：46

作者：

Du, Wenya ^{[1
]}

Zhang, Lin ^{[1
]}

Suh, Emma ^{[1
,2
]}

Lin, Dabin ^{[3
]}

Marcus, Colin ^{[1
,4
]}

Ozkan, Lara ^{[1
,4
]}

Ahuja, Avani ^{[1
,2
]}

Fernandez, Sara ^{[1
,5
]}

Shuvo, Ikra Iftekhar ^{[1
]}

Sadat, David ^{[1
]}

Liu, Weiguo ^{[3
]}

Li, Fei ^{[6
]}

Chandrakasan, Anantha P. ^{[4
]}

Ozmen, Tolga ^{[7
]}

Dagdeviren, Canan ^{[1
]}

机构：

[1] MIT, Media Lab, Cambridge, MA 02139 USA

[2] MIT, Dept Mech Engn, Cambridge, MA 02139 USA

[3] Xian Technol Univ, Sch Optoelect Engn, Xian 710021, Peoples R China

[4] MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA

[5] MIT, Dept Mat Sci & Engn, Cambridge, MA 02142 USA

[6] Xi An Jiao Tong Univ, Sch Elect Sci & Engn, Elect Mat Res Lab, Xian 710049, Peoples R China

[7] Harvard Med Sch, Massachusetts Gen Hosp, Div Surg Oncol, Boston, MA 02114 USA

来源：

SCIENCE ADVANCES | 2023年 / 9卷 / 30期

关键词：

CANCER; TRANSDUCERS; MAMMOGRAPHY; PERFORMANCE; CERAMICS; CRYSTALS; DESIGN; BODY; SIZE;

D O I：

10.1126/sciadv.adh5325

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Ultrasound is widely used for tissue imaging such as breast cancer diagnosis; however, fundamental challenges limit its integration with wearable technologies, namely, imaging over large-area curvilinear organs. We introduced a wearable, conformable ultrasound breast patch (cUSBr-Patch) that enables standardized and reproducible image acquisition over the entire breast with less reliance on operator training and applied transducer compression. A nature-inspired honeycomb-shaped patch combined with a phased array is guided by an easy-to-operate tracker that provides for large-area, deep scanning, and multiangle breast imaging capability. The in vitro studies and clinical trials reveal that the array using a piezoelectric crystal [Yb/Bi-Pb(In1/2Nb1/2)O-3-Pb(Mg1/3Nb2/3)O-3-PbTiO3] (Yb/Bi-PIN-PMN-PT) exhibits a sufficient contrast resolution (similar to 3 dB) and axial/lateral resolutions of 0.25/1.0 mm at 30 mm depth, allowing the observation of small cysts (similar to 0.3 cm) in the breast. This research develops a first-of-its-kind ultrasound technology for breast tissue scanning and imaging that offers a noninvasive method for tracking real-time dynamic changes of soft tissue.

引用

页数：13

共 70 条

[1] THE DESIGN AND CHARACTERIZATION OF AN ULTRASOUND PHASED ARRAY SUITABLE FOR DEEP TISSUE HYPERTHERMIA [J].