Natriuretic Peptides: Role in the Diagnosis and Management of Heart Failure: A Scientific Statement From the Heart Failure Association of the European Society of Cardiology, Heart Failure Society of America and Japanese Heart Failure Society

被引：82

作者：

Tsutsui, Hiroyuki ^{[1
]}

Albert, Nancy M. ^{[2
]}

Coats, Andrew J. S. ^{[3
,4
]}

Anker, Stefan D. ^{[5
,6
,7
]}

Bayes-Genis, Antoni ^{[8
,9
]}

Butler, Javed ^{[10
,11
]}

Chioncel, Ovidiu ^{[12
]}

Defilippi, Christopher R. ^{[13
]}

Drazner, Mark H. ^{[14
]}

Felker, G. Michael ^{[15
]}

Filippatos, Gerasimos ^{[16
,17
]}

Fiuzat, Mona

Ide, Tomomi ^{[1
]}

Januzzi, James L., Jr. ^{[18
,19
]}

Kinugawa, Koichiro ^{[20
]}

Kuwahara, Koichiro ^{[21
]}

Matsue, Yuya ^{[22
]}

Mentz, Robert J. ^{[15
,23
]}

Metra, Marco ^{[24
,25
]}

Pandey, Ambarish ^{[26
]}

Rosano, Giuseppe ^{[27
]}

Saito, Yoshihiko ^{[28
,29
]}

Sakata, Yasushi ^{[30
]}

Sato, Naoki ^{[31
]}

Seferovic, Petar M. ^{[32
]}

Teerlink, John ^{[33
,34
]}

Yamamoto, Kazuhiro ^{[35
]}

Yoshimura, Michihiro ^{[36
]}

机构：

[1] Kyushu Univ, Dept Cardiovasc Med, Fac Med Sci, Fukuoka, Japan

[2] Cleveland Clin, Res & Innovat ursing Inst, Kaufman Ctr Heart Failure Heart, Vasc & Thorac Inst, Cleveland, OH USA

[3] Univ Warwick, Warwick, England

[4] Monash Univ, Clayton, Australia

[5] Berlin Inst Hlth Ctr Regenerat Therapies

[6] Charite Univ Med Berlin, German Ctr Cardiovasc Res partner site Berlin, Berlin, Germany

[7] Wroclaw Med Univ, Inst Heart Dis, Wroclaw, Poland

[8] Hosp Germans Trias i Pujol, Heart Inst, CIBERCV, Badalona, Spain

[9] Univ Autonoma Barcelona, Barcelona, Spain

[10] Baylor Scott & White Res Inst, Dallas, TX USA

[11] Univ Mississippi, Jackson, MS USA

[12] Univ Med & Pharm Carol Davila, Emergency Inst Cardiovasc Dis Prof CC Ilies Bucha, Bucharest, Romania

[13] Inova Heart & Vasc Inst, Falls Church, VA USA

[14] Univ Texas Southwestern Med Ctr, Clin Chief Cardiol, Dept Internal Med, Div Cardiol, Dallas, TX USA

[15] Duke Univ, Sch Med, Div Cardiol, Durham, NC USA

[16] Athens Univ Hosp Attikon, Sch Med Natl, Athens, Greece

[17] Kapodistrian Univ Athens, Athens Univ Hosp Attikon, Athens, Greece

[18] Harvard Med Sch, Massachusetts Gen Hosp, Boston, MA USA

[19] Baim Inst Clin Res, Boston, MA USA

[20] Toyama Univ, Fac Med, Dept Internal Med 2, Toyama, Japan

[21] Shinshu Univ, Sch Med, Dept Cardiovasc Med, Matsumoto, Japan

[22] Juntendo Univ, Grad Sch Med, Dept Cardiovascc Biol & Med, Tokyo, Japan

[23] Duke Clin Res Inst, Durham, NC USA

[24] Univ Brescia, Cardiol, ASST Spedali Civili, Brescia, Italy

[25] Univ Brescia, Dept Med & Surg Specialties, Radiol Sci & Publ Hlth, Brescia, Italy

[26] Univ Texas Southwestern, Dept Med, Div Cardiol, Dallas, TX USA

[27] IRCCS San Raffaele Pisana, Ctr Clin & Basic Res, Dept Med Sci, Rome, Italy

[28] Nara Med Univ, Dept Cardiovasc Med, Kashihara, Japan

[29] Nara Prefecture Seiwa Med Ctr, Sango, Japan

[30] Osaka Univ, Grad Sch Med, Dept Cardiovasc Med, Osaka, Japan

[31] Kawaguchi Cardiovasc & Resp Hosp, Dept Cardiovasc Med, Kawaguchi, Japan

[32] Univ Belgrade, Fac Med, Serbian Acad Sci & Arts & Heart Failure Ctr, Med Ctr, Belgrade, Serbia

[33] San Francisco VA Med Ctr, Sect Cardiol, San Francisco, CA USA

[34] Univ Calif San Francisco, Sch Med, San Francisco, CA USA

[35] Tottori Univ, Dept Cardiovasc Med & Endocrinol & Metab, Fac Med, Yonago, Japan

[36] Jikei Univ, Sch Med, Dept Internal Med, Div Cardiol, Tokyo, Japan

来源：

EUROPEAN JOURNAL OF HEART FAILURE | 2023年 / 25卷 / 05期

关键词：

Heart failure; natriuretic peptides; diagnosis; therapy; REDUCED EJECTION FRACTION; NT-PROBNP; CARDIOVASCULAR MORTALITY; EMERGENCY-DEPARTMENT; INCLUSION CRITERIA; 6-MONTH MORTALITY; POOLED ANALYSIS; TERM PROGNOSIS; GUIDED THERAPY; BNP LEVELS;

D O I：

10.1002/ejhf.2848

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Natriuretic peptides, brain (B-type) natriuretic peptide (BNP) and N-terminal prohormone of brain natriuretic peptide (NT-proBNP) are globally and most often used for the diagnosis of heart failure (HF). In addition, they can have an important complementary role in the risk stratification of its prognosis. Since the development of angiotensin receptor neprilysin inhibitors (ARNIs), the use of natriuretic peptides as therapeutic agents has grown in importance. The present document is the result of the Trilateral Cooperation Project among the Heart Failure Association of the European Society of Cardiology, the Heart Failure Society of America and the Japanese Heart Failure Society. It represents an expert consensus that aims to provide a comprehensive, up-to-date perspective on natriuretic peptides in the diagnosis and management of HF, with a focus on the following main issues: (1) history and basic research: discovery, production and cardiovascular protection; (2) diagnostic and prognostic biomarkers: acute HF, chronic HF, inclusion/endpoint in clinical trials, and natriuretic peptides-guided therapy; (3) therapeutic use: nesiritide (BNP), carperitide (ANP) and ARNIs; and (4) gaps in knowledge and future directions.

引用

页码：616 / 631

页数：16

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