Fluoride releasing in polymer blends of poly(ethylene oxide) and poly(methyl methacrylate)

被引：0

作者：

Wang, Tianxiao ^{[1
]}

Li, Menghong ^{[1
]}

Gu, Ziyan ^{[1
]}

Qu, Chengjuan ^{[1
]}

Segervald, Jonas ^{[2
]}

Salh, Roushdey ^{[2
]}

Wagberg, Thomas ^{[2
]}

Wang, Jia ^{[2
]}

Kou, Wen ^{[1
]}

机构：

[1] Umea Univ, Dept Odontol, Umea, Sweden

[2] Umea Univ, Dept Phys, Umea, Sweden

来源：

FRONTIERS IN CHEMISTRY | 2024年 / 12卷

基金：

瑞典研究理事会;

关键词：

dental materials; polymethyl methacrylate; polyethylene oxide; fluoride ion release; polymer blend; MOLECULAR-WEIGHT; CARIES; PEO; ELECTROLYTES; COMPOSITES; MAGNESIUM; TOXICITY; DISEASES; INSITU; PMMA;

D O I：

10.3389/fchem.2024.1356029

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Introduction: Polymethyl methacrylate is a polymer commonly used in clinical dentistry, including denture bases, occlusal splints and orthodontic retainers.Methods: To augment the polymethyl methacrylate-based dental appliances in counteracting dental caries, we designed a polymer blend film composed of polymethyl methacrylate and polyethylene oxide by solution casting and added sodium fluoride.Results: Polyethylene oxide facilitated the dispersion of sodium fluoride, decreased the surface average roughness, and positively influenced the hydrophilicity of the films. The blend film made of polymethyl methacrylate, polyethylene oxide and NaF with a mass ratio of 10: 1: 0.3 showed sustained release of fluoride ions and acceptable cytotoxicity. Antibacterial activity of all the films to Streptococcus mutans was negligible.Discussion: This study demonstrated that the polymer blends of polyethylene oxide and polymethyl methacrylate could realize the relatively steady release of fluoride ions with high biocompatibility. This strategy has promising potential to endow dental appliances with anti-cariogenicity.

引用

页数：10

共 49 条

[1]

Akiniwa K, 1997, FLUORIDE, V30, P89

[2]

Amina S., 2019, Int. J. Oral Health Dent, V5, P63, DOI [10.18231/j.ijohd.2019.016, DOI 10.18231/J.IJOHD.2019.016]

[3] POLY(ETHYLENE OXIDE) (PEO) AND DIFFERENT MOLECULAR-WEIGHT PEO BLENDS MONOLITHIC DEVICES FOR DRUG RELEASE [J].

APICELLA, A ;

CAPPELLO, B ;

DELNOBILE, MA ;

LAROTONDA, MI ;

MENSITIERI, G ;

NICOLAI, L .

BIOMATERIALS, 1993, 14 (02) :83-90

[4]

Arlappa N., 2013, International Journal of Research and Development of Health, V1, P97

[5] Fluoride in drinking water: A review on the status and stress effects [J].

Ayoob, S. ;

Gupta, A. K. .

CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY, 2006, 36 (06) :433-487

[6] Streptococcus mutans biofilm changes surface-topography of resin composites [J].

Beyth, Nurit ;

Bahir, Ran ;

Matalon, Shlomo ;

Domb, Abraham J. ;

Weiss, Ervin I. .

DENTAL MATERIALS, 2008, 24 (06) :732-736

[7] Evaluation of Biocompatibility Using In Vitro Methods: Interpretation and Limitations [J].

Bruinink, Arie ;

Luginbuehl, Reto .

TISSUE ENGINEERING III: CELL-SURFACE INTERACTIONS FOR TISSUE CULTURE, 2012, 126 :117-152

[8] Compliance monitoring via a Bluetooth-enabled retainer: A prospective clinical pilot study [J].

Castle, Eric ;

Chung, Philip ;

Behfar, Mohammad H. ;

Chen, Matthew ;

Gao, Jonathan ;

Chiu, Nicholas ;

Nelson, Gerald ;

Roy, Shuvo ;

Oberoi, Snehlata .

ORTHODONTICS & CRANIOFACIAL RESEARCH, 2019, 22 :149-153

[9] Effect of modified Fe3O4 nanoparticles on the preparation of PMMA/Fe3O4 microspheres via suspension polymerization [J].

Chen, Tao ;

Zhao, Yuan ;

Zhao, Long ;

Du, Jifu ;

Xie, Cong .

2017 3RD INTERNATIONAL CONFERENCE ON ENVIRONMENTAL SCIENCE AND MATERIAL APPLICATION (ESMA2017), VOLS 1-4, 2018, 108

[10] In Vitro Evaluation of Structural Factors Favouring Bacterial Adhesion on Orthodontic Adhesive Resins [J].

Condo, Roberta ;

Mampieri, Gianluca ;

Pasquantonio, Guido ;

Giancotti, Aldo ;

Pirelli, Paola ;

Cataldi, Maria Elena ;

La Rocca, Serena ;

Leggeri, Andrea ;

Notargiacomo, Andrea ;

Maiolo, Luca ;

De Filippis, Patrizia ;

Cerroni, Loredana .

MATERIALS, 2021, 14 (10)

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