Parental telomeres implications on immune senescence of newborns

被引：0

作者：

Farrukh, Sadia ^{[1
]}

Baig, Saeeda ^{[1
]}

机构：

[1] Ziauddin Univ, Dept Biochem, Karachi, Pakistan

来源：

AMERICAN JOURNAL OF CLINICAL AND EXPERIMENTAL IMMUNOLOGY | 2023年 / 12卷 / 05期

关键词：

Telomere; immune senescence; telomerase; newborn; LENGTH; ASSOCIATION;

D O I：

暂无

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Telomere, the biological chronometer, and its effect on the immune system considerably varies among individuals. During pregnancy, multiple risk factors affect telomere reprogramming during fetal life which can lead to health disparities in newborns. These changes may cause a long-term impact on the telomere genetics of the newborn and become a reason for lifelong health implications and immune senescence. Therefore, telomere shortening in parents due to genetic variation may act as a hallmark of immune senescence and aging in their newborns.

引用

页码：81 / 86

页数：6

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