Tubular nanomaterials for bone tissue engineering

被引:27
作者
Akiyama, Naomi [1 ]
Patel, Kapil D. [2 ]
Jang, Eun Jo [3 ]
Shannon, Mark R. [4 ]
Patel, Rajkumar [5 ]
Patel, Madhumita [6 ]
Perriman, Adam Willis [2 ,7 ,8 ]
机构
[1] Cooper Union Adv Sci & Art, Dept Chem Engn, New York, NY 10003 USA
[2] Univ Bristol, Sch Cellular & Mol Med, Bristol BS8 1TD, England
[3] Yonsei Univ, Underwood Int Coll, Integrated Sci & Engn Div ISED, Nano Sci & Engn NSE, Yeonsu gu, Incheon 21983, South Korea
[4] Univ Bristol, Bristol Composites Inst BCI, Bristol BS8 1UP, England
[5] Yonsei Univ, Underwood Int Coll, Integrated Sci & Engn Div ISED, Energy & Environm Sci & Engn EESE, Yeonsu gu, Incheon 21983, South Korea
[6] Ewha Womans Univ, Dept Chem & Nanosci, 52 Ewhayeodae gil,Seodaemun gu, Seoul 03760, South Korea
[7] Australian Natl Univ, Res Sch Chem, Canberra, ACT 2601, Australia
[8] Australian Natl Univ, John Curtin Sch Med Res, Canberra, ACT 2601, Australia
基金
英国工程与自然科学研究理事会;
关键词
HALLOYSITE CLAY NANOTUBES; MESENCHYMAL STEM-CELLS; WALLED CARBON NANOTUBES; IN-VITRO; MESOPOROUS SILICA; OSTEOGENIC DIFFERENTIATION; HYDROXYAPATITE NANOTUBES; MECHANICAL-PROPERTIES; COMPOSITE SCAFFOLDS; ELECTROPHORETIC COATINGS;
D O I
10.1039/d3tb00905j
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Nanomaterial composition, morphology, and mechanical performance are critical parameters for tissue engineering. Within this rapidly expanding space, tubular nanomaterials (TNs), including carbon nanotubes (CNTs), titanium oxide nanotubes (TNTs), halloysite nanotubes (HNTs), silica nanotubes (SiNTs), and hydroxyapatite nanotubes (HANTs) have shown significant potential across a broad range of applications due to their high surface area, versatile surface chemistry, well-defined mechanical properties, excellent biocompatibility, and monodispersity. These include drug delivery vectors, imaging contrast agents, and scaffolds for bone tissue engineering. This review is centered on the recent developments in TN-based biomaterials for structural tissue engineering, with a strong focus on bone tissue regeneration. It includes a detailed literature review on TN-based orthopedic coatings for metallic implants and composite scaffolds to enhance in vivo bone regeneration.
引用
收藏
页码:6225 / 6248
页数:24
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