Antiparkinsonian Medication Reconciliation as a Strategy to Improve Safety by Preventing Medication Errors

被引:3
作者
Viudez-Martinez, Adrian [1 ]
Ramirez-Lopez, Ana [1 ]
Lopez-Nieto, Javier [1 ]
Climent-Grana, Eduardo [1 ]
Riera, Geronima [1 ]
机构
[1] Hosp Gen Univ Dr Balmis, Pharm Dept, Inst Invest Biomed & Sanitaria Alicante ISABIAL, Alicante, Spain
来源
MOVEMENT DISORDERS CLINICAL PRACTICE | 2023年 / 10卷 / 07期
关键词
medication errors; Parkinson's disease; medication reconciliation; safety; therapeutics; PARKINSONS-DISEASE PATIENTS; HOSPITALIZATION; DRUGS; RISK; PEOPLE; BURDEN;
D O I
10.1002/mdc3.13789
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
BackgroundAbout 70% of neurologists report that PD patients do not get their medication properly when hospitalized, and 33% are prescribed contraindicated drugs. ObjectivesTo execute medication reconciliation (MedRec) focused on antiparkinsonian drugs to identify, characterize and, eventually, prevent medication errors, thus promoting therapeutic quality and safety in daily practice. MethodsAn interventional, single-center, 1 year, prospective study. All the patients who were hospitalized and had, at least, one active prescription containing an antiparkinsonian drug at hospital admission were included. MedRec was performed by following a three-phased check: inpatient electronic prescription validation after assessing the outpatient medication schedule, review of the latest clinical report emitted by the Neurology Department/General Practitioner, and pharmacist-driven interview of the patient and/or caregiver to confirm the information regarding medication gathered. ResultsA total of 171 admission episodes from 132 patients were registered (February 1, 2021, and January 31, 2022). Of 224 prescription lines involving antiparkinsonian drugs, 179 contained, at least, one medication error (59.8%). Commission errors (91.62%) were more frequent than omitted drugs (8.38%). The most common medication errors were related to timing (41.90%), frequency (21.23%), and dosing (19.55%). The implementation of this program prevented the erroneous administration of 2716 antiparkinsonian doses, 60% of the total number of doses prescribed. Interestingly, a significant relationship between the number of medication errors and having levodopa prescribed was evidenced (P < 0.05). A contraindicated drug was prescribed in almost one-third of the episodes (29.82%). ConclusionsClinical pharmacists' implementation of an antiparkinsonians reconciliation program sharply reduced medication errors and prescription of contraindicated drugs.
引用
收藏
页码:1090 / 1098
页数:9
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