Use of intravenous buprenorphine microdosing to initiate medication for opioid use disorder in a patient with co-occurring pain: case report

被引：1

作者：

Bodnar, Alia ^{[1
]}

Diffenderffer, Christine ^{[1
]}

Jablonski, Lindsay A. ^{[2
]}

Bai, Eric ^{[1
]}

Stewart, Rosalyn W. ^{[1
]}

机构：

[1] Johns Hopkins Univ, Dept Med, 601 N Caroline St,Suite 7-143, Baltimore, MD 21287 USA

[2] Johns Hopkins Univ Hosp, Dept Pharm, Baltimore, MD USA

来源：

JOURNAL OF ADDICTIVE DISEASES | 2024年 / 42卷 / 04期

关键词：

Buprenorphine microdosing; low-dose buprenorphine induction; opioid use disorder; acute pain; case report;

D O I：

10.1080/10550887.2023.2285201

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

IntroductionBuprenorphine is used to treat opioid use disorder (OUD). However, therapy is often disrupted during acute pain episodes, and re-initiation is often deferred due to intolerable interruption in opioid analgesics. This case report describes a unique strategy for inducing buprenorphine without stopping opioid analgesics.CaseOne patient with OUD and acute pain was initiated on buprenorphine using intravenous microdosing without precipitated withdrawal or pain exacerbation. Full agonist opioids were successfully weaned after discharge and the patient was linked with a community-based treatment program.ConclusionThis case describes use of intravenous buprenorphine to treat OUD and acute pain without adverse consequences.

引用

页码：567 / 571

页数：5

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