Massive ossifying fibroma of mandible: A case report and review of the literature

Key Clinical MessageBenign fibro-osseous neoplasm. Massive size is rarely reported. May be confused with other pathologies such as fibrous dysplasia or osteosarcoma. Aggressive nature and high recurrence pose management challenges. Treated by surgery.AbstractOssifying fibroma is a benign fibro-osseous neoplasm. It can affect both mandible and maxilla. Precise diagnosis can be challenging due to significant overlap of clinicopathological features with other neoplasms. Case reports with massive tumor sizes as presented in our case are uncommon. Huge tumor size can cause alarm for other pathologies such as osteosarcoma. The radiological tests should reassure the attending practitioner and histological examination confirm the diagnosis. The aim of the present report is to discuss a case of a giant ossifying fibroma in a 13-year-old male child. He presented with a progressive mandibular mass for 4 years. Clinical, radiological, and pathological characteristics and surgical treatment approaches are further discussed. This is one of the rare cases of massive ossifying fibroma in the English literature. A patient with a massive mandibular tumor causing facial asymmetry (upper left), CT scan imaging reveals an expansile mass causing bone erosion and tooth loss (upper right), histopathology showing a benign fibro-osseous nature of the lesion (lower left), photographs of the patient during and after surgery (lower right).image