Evaluation of Static and Dynamic Pupillary Functions in Early-Stage Primary Open Angle Glaucoma

被引:2
作者
Bayraktar, Serdar [1 ,2 ]
Hondur, Goezde [1 ]
Sekeroglu, Mehmet Ali [1 ]
Sen, Emine [1 ]
机构
[1] Univ Hlth Sci, Ankara Ulucanlar Eye Training & Res Hosp, Ankara, Turkiye
[2] Ulucanlar Eye Training & Res Hosp, Ankara, Turkiye
关键词
automated pupillometry; dynamic pupillometry; early-stage glaucoma; pupil; static pupillometry; RETINAL GANGLION-CELLS; RESPONSES DRIVEN; LIGHT; TENSION; MODEL; SIZE;
D O I
10.1097/IJG.0000000000002212
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Precis:The dynamic parameters of the pupil, evaluated with an automated pupillometry device, differ in newly diagnosed early-stage primary open angle glaucoma (POAG) patients compared with healthy individuals, and this may guide us in early diagnosis and follow-up of glaucoma. Introduction and Aim:To quantitatively determine static and dynamic pupillary functions in treatment-naive, newly diagnosed early-stage POAG patients and compare them with healthy controls. Methods:Forty eye of forty subjects with early POAG were compared with 71 eye of 71 age- matched and sex-matched healthy controls in terms of static and dynamic pupillary functions in this prospective and cross-sectional study. Static and dynamic pupillary functions were obtained with an automated pupillometry device. Static pupillometry parameters are pupil diameter (mm) in high photopic (100 cd/m(2)), low photopic (10 cd/m(2)), mesopic (1 cd/m(2)), and scotopic (0.1 cd/m(2)) light conditions. Dynamic pupillometry parameters are resting diameter (mm), amplitude (mm), latency (ms), duration (ms), and velocity (mm/s) of pupil contraction and dilation. Measured data were evaluated and compared with t test for independent groups. Results:Duration of pupil contraction was lower, (P=0.04) latency of pupil dilation time was longer, (P=0.03) duration of pupil dilation was shorter (P=0.04) and velocity of pupil dilation was lower (P=0.02) in the POAG group. There was no significant difference between the 2 groups in terms of static pupillometry characteristics and the resting pupil diameter (P>0.05 for all values). Conclusion:These results suggest that dynamic pupillary light responses may be affected in early-stage POAG compared with the normal population. Longitudinal studies with larger series are needed to better understand the quantitative changes in dynamic pupillometry functions in early-stage POAG.
引用
收藏
页码:E90 / E94
页数:5
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