Scoring System for Predicting No Hearing Recovery in Unilateral Idiopathic Sudden Sensorineural Hearing Loss

被引:0
|
作者
Safitri, Eka Dian [1 ,5 ]
Harimurti, Kuntjoro [1 ,2 ]
Ranakusuma, Respati W. [1 ]
Alviandi, Widayat [3 ]
Bashirudin, Jenny [3 ]
Savitri, Ary I. [4 ]
机构
[1] Univ Indonesia, Cipto Mangunkusumo Gen Hosp, Fac Med, Clin Epidemiol & Evidence Based Med Unit, Jakarta, Indonesia
[2] Univ Indonesia, Cipto Mangunkusumo Hosp, Dept Internal Med, Fac Med, Jakarta, Indonesia
[3] Univ Indonesia, Dr Cipto Mangunkusumo Hosp, Fac Med, Dept Ear Nose Throat Head & Neck Surg, Jakarta, Indonesia
[4] Univ Med Ctr, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands
[5] Fac Med Univ Indonesia Jl Diponegoro no, Cipto Mangunkusumo Hosp, Clin Epidemiol & Evidence Based Med Unit, Fac Med, Jl Diponegoro. 71, Jakarta 10430, Indonesia
关键词
idiopathic sudden sensory neural hearing loss; score system; no hearing recovery; STEROID-THERAPY; METAANALYSIS; DYSFUNCTION; TINNITUS;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: The varying degrees of hearing recovery in idiopathic sudden sensory neural hearing loss (ISSHL) patients indicate the need of model to predict no hearing recovery. We aimed to aid in the counseling of ISSHL patients about their recovery chances by developing a simple clinical scoring system to predict no hearing recovery using clinical information available at first visit.Methods: A retrospective cohort study, using medical records was conducted from January 2017-May 2019 in Cipto Mangunkusumo General Hospital and Proklamasi Ear, Nose, Throat, Head and Neck (ENT-HN) Surgery Specialized Hospital in Jakarta, Indonesia. The outcome measure is no hearing recovery and we built the prediction score developed based on multiple logistic regression analyses and tested for discriminative ability. There were 183 adults unilateral ISSHL patients included in the study.Results: The proportion of no hearing recovery was 56%. The independent predictors were older age 30-60 years and >60 years old (Odds Ratio 4.0; 95% CI 1.4-11.8; p=0.012 and OR 5.3; 95% CI 1.5-18.4; p=0.008, respectively) as compared with 18-<30 years old, later onset (onset 15-60 days and >60 days had OR 5.4; 95% CI 1.7-16.9; p=0.004 and OR 12.6; 95% CI 2.9-54.6; p=0.001, respectively, as compared with onset < 3 days), and presence of vertigo (OR 2.3; 95% CI 1.1-4.6; p=0.026). Prediction scores ranged from 3 to 12, with three categories for age, four for onset, and two for the presence of vertigo. The predictions showed adequate calibration and good discriminative ability (AUC 0.77).Conclusion: Using information of age, onset and presence of vertigo at first visit, ISSHL patient with increased risk of no hearing recovery can be identified with moderate accuracy. This prediction model could help clinician in predicting patients' prognosis.
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收藏
页码:285 / 295
页数:11
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