共 100 条
[1]
Administration USFD, 2023, About Alternative Methods
[2]
Administration USFD, Innovative science and technology approaches for new drugs (ISTAND) pilot program 2023
[3]
Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations
[J].
Albrecht, Wiebke
;
Kappenberg, Franziska
;
Brecklinghaus, Tim
;
Stoeber, Regina
;
Marchan, Rosemarie
;
Zhang, Mian
;
Ebbert, Kristina
;
Kirschner, Hendrik
;
Grinberg, Marianna
;
Leist, Marcel
;
Moritz, Wolfgang
;
Cadenas, Cristina
;
Ghallab, Ahmed
;
Reinders, Joerg
;
Vartak, Nachiket
;
van Thriel, Christoph
;
Golka, Klaus
;
Tolosa, Laia
;
Castell, Jose V.
;
Damm, Georg
;
Seehofer, Daniel
;
Lampen, Alfonso
;
Braeuning, Albert
;
Buhrke, Thorsten
;
Behr, Anne-Cathrin
;
Oberemm, Axel
;
Gu, Xiaolong
;
Kittana, Naim
;
van de Water, Bob
;
Kreiling, Reinhard
;
Fayyaz, Susann
;
van Aerts, Leon
;
Smedsrod, Bard
;
Ellinger-Ziegelbauer, Heidrun
;
Steger-Hartmann, Thomas
;
Gundert-Remy, Ursula
;
Zeigerer, Anja
;
Ullrich, Anett
;
Runge, Dieter
;
Lee, Serene M. L.
;
Schiergens, Tobias S.
;
Kuepfer, Lars
;
Aguayo-Orozco, Alejandro
;
Sachinidis, Agapios
;
Edlund, Karolina
;
Gardner, Iain
;
Rahnenfuehrer, Joerg
;
Hengstler, Jan G.
.
ARCHIVES OF TOXICOLOGY,
2019, 93 (06)
:1609-1637

Albrecht, Wiebke
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机构:
Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Kappenberg, Franziska
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机构:
TU Dortmund Univ, Dept Stat, D-44227 Dortmund, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Brecklinghaus, Tim
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机构:
Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Stoeber, Regina
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机构:
Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Marchan, Rosemarie
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h-index: 0
机构:
Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Zhang, Mian
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机构:
Simcyp, Sheffield, S Yorkshire, England Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Ebbert, Kristina
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机构:
Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Kirschner, Hendrik
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机构:
Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Grinberg, Marianna
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h-index: 0
机构:
TU Dortmund Univ, Dept Stat, D-44227 Dortmund, Germany
Merck KGaA, Dept R&D Global Biostat Epidemiol & Med Writing, Darmstadt, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

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Moritz, Wolfgang
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机构:
InSphero AG, Wagistr 27, CH-8952 Schlieren, Switzerland Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Cadenas, Cristina
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机构:
Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Ghallab, Ahmed
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h-index: 0
机构:
Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany
South Valley Univ, Fac Vet Med, Dept Forens Med & Toxicol, Qena, Egypt Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Reinders, Joerg
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机构:
Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Vartak, Nachiket
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机构:
Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

van Thriel, Christoph
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机构:
Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Golka, Klaus
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机构:
Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Tolosa, Laia
论文数: 0 引用数: 0
h-index: 0
机构:
Inst Invest Sanitaria La Fe, Expt Hepatol Unit, Valencia, Spain Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Castell, Jose V.
论文数: 0 引用数: 0
h-index: 0
机构:
Inst Invest Sanitaria La Fe, Expt Hepatol Unit, Valencia, Spain Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Damm, Georg
论文数: 0 引用数: 0
h-index: 0
机构:
Charite Univ Med Berlin, Dept Gen Visceral & Transplantat Surg, D-13353 Berlin, Germany
Univ Leipzig, Dept Hepatobiliary Surg & Visceral Transplantat, Leipzig, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Seehofer, Daniel
论文数: 0 引用数: 0
h-index: 0
机构:
Charite Univ Med Berlin, Dept Gen Visceral & Transplantat Surg, D-13353 Berlin, Germany
Univ Leipzig, Dept Hepatobiliary Surg & Visceral Transplantat, Leipzig, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Lampen, Alfonso
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机构:
German Fed Inst Risk Assessment, Dept Food Safety, Max Dohrn Str 8-10, D-10589 Berlin, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Braeuning, Albert
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机构:
German Fed Inst Risk Assessment, Dept Food Safety, Max Dohrn Str 8-10, D-10589 Berlin, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Buhrke, Thorsten
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机构:
German Fed Inst Risk Assessment, Dept Food Safety, Max Dohrn Str 8-10, D-10589 Berlin, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Behr, Anne-Cathrin
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h-index: 0
机构:
German Fed Inst Risk Assessment, Dept Food Safety, Max Dohrn Str 8-10, D-10589 Berlin, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Oberemm, Axel
论文数: 0 引用数: 0
h-index: 0
机构:
German Fed Inst Risk Assessment, Dept Food Safety, Max Dohrn Str 8-10, D-10589 Berlin, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Gu, Xiaolong
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机构:
Yunnan Agr Univ, Coll Vet Med, Kunming 650201, Yunnan, Peoples R China Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

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van de Water, Bob
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机构:
Leiden Univ, LACDR, Div Drug Discovery & Safety, Einsteinweg 55,POB 9502, NL-2300 RA Leiden, Netherlands Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Kreiling, Reinhard
论文数: 0 引用数: 0
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机构:
Clariant Prod Deutschland GmbH, Unisyspk 1, D-65843 Sulzbach, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Fayyaz, Susann
论文数: 0 引用数: 0
h-index: 0
机构:
Clariant Prod Deutschland GmbH, Unisyspk 1, D-65843 Sulzbach, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

van Aerts, Leon
论文数: 0 引用数: 0
h-index: 0
机构:
Med Evaluat Board Pharmacol Toxicol Pharmacokinec, Utrecht, Netherlands Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Smedsrod, Bard
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Tromso, Vasc Biol Res Grp, Dept Med Biol, NO-9037 Tromso, Norway Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Ellinger-Ziegelbauer, Heidrun
论文数: 0 引用数: 0
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机构:
Bayer AG, Invest Toxicol, Drug Discovery, Pharmaceut, D-42096 Wuppertal, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Steger-Hartmann, Thomas
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机构:
Bayer AG, Invest Toxicol, Drug Discovery, Pharmaceut, D-42096 Wuppertal, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Gundert-Remy, Ursula
论文数: 0 引用数: 0
h-index: 0
机构:
Charite Univ Med Berlin, Inst Clin Pharmacol & Toxicol, Berlin, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Zeigerer, Anja
论文数: 0 引用数: 0
h-index: 0
机构:
Helmholtz Ctr Munich, Inst Diabet & Canc, D-85764 Neuherberg, Germany
Heidelberg Univ Hosp, Joint Heidelberg IDC Translat Diabet Program, Inner Med 1, Heidelberg, Germany
German Ctr Diabet Res DZD, D-85764 Neuherberg, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Ullrich, Anett
论文数: 0 引用数: 0
h-index: 0
机构:
Primacyt Cell Culture Technol GmbH, Schwerin, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Runge, Dieter
论文数: 0 引用数: 0
h-index: 0
机构:
Primacyt Cell Culture Technol GmbH, Schwerin, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Lee, Serene M. L.
论文数: 0 引用数: 0
h-index: 0
机构:
Ludwig Maximilians Univ Munchen, Dept Gen Visceral & Transplant Surg, Human Tissue & Cell Res Fdn, Biobank, Munich, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Schiergens, Tobias S.
论文数: 0 引用数: 0
h-index: 0
机构:
Ludwig Maximilians Univ Munchen, Dept Gen Visceral & Transplant Surg, Human Tissue & Cell Res Fdn, Biobank, Munich, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Kuepfer, Lars
论文数: 0 引用数: 0
h-index: 0
机构:
Bayer AG, Syst Pharmacol, Leverkusen, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Aguayo-Orozco, Alejandro
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Copenhagen, NNF Ctr Prot Res, Translat Dis Syst Biol, Copenhagen, Denmark Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

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Edlund, Karolina
论文数: 0 引用数: 0
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机构:
Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Gardner, Iain
论文数: 0 引用数: 0
h-index: 0
机构:
Simcyp, Sheffield, S Yorkshire, England Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Rahnenfuehrer, Joerg
论文数: 0 引用数: 0
h-index: 0
机构:
TU Dortmund Univ, Dept Stat, D-44227 Dortmund, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany

Hengstler, Jan G.
论文数: 0 引用数: 0
h-index: 0
机构:
Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany Tech Univ Dortmund IfADo, Leibniz Res Ctr Working Environm & Human Factors, Ardeystr 67, D-44139 Dortmund, Germany
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Bile Acid Sulfation: A Pathway of Bile Acid Elimination and Detoxification
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Alnouti, Yazen
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TOXICOLOGICAL SCIENCES,
2009, 108 (02)
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Alnouti, Yazen
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机构:
Univ Nebraska, Med Ctr, Coll Pharm, Dept Pharmaceut Sci, Omaha, NE 68198 USA Univ Nebraska, Med Ctr, Coll Pharm, Dept Pharmaceut Sci, Omaha, NE 68198 USA
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Chemical-PDMS binding kinetics and implications for bioavailability in microfluidic devices
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Auner, Alexander W.
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Vanderbilt Univ, Dept Phys & Astron, Nashville, TN 37235 USA Vanderbilt Univ, Dept Phys & Astron, Nashville, TN 37235 USA

Tasneem, Kazi M.
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h-index: 0
机构:
Vanderbilt Univ, Dept Chem & Biomol Engn, 221 Kirkland Hall, Nashville, TN 37235 USA Vanderbilt Univ, Dept Phys & Astron, Nashville, TN 37235 USA

Markov, Dmitry A.
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h-index: 0
机构:
Vanderbilt Univ, Dept Biomed Engn, Nashville, TN 37235 USA Vanderbilt Univ, Dept Phys & Astron, Nashville, TN 37235 USA

McCawley, Lisa J.
论文数: 0 引用数: 0
h-index: 0
机构:
Vanderbilt Univ, Dept Biomed Engn, Nashville, TN 37235 USA Vanderbilt Univ, Dept Phys & Astron, Nashville, TN 37235 USA

Hutson, M. Shane
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h-index: 0
机构:
Vanderbilt Univ, Dept Phys & Astron, Nashville, TN 37235 USA Vanderbilt Univ, Dept Phys & Astron, Nashville, TN 37235 USA
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DRUG METABOLISM AND DISPOSITION,
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Baker, Thomas K.
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机构:
Eli Lilly, Invest Toxicol, Indianapolis, IN USA Eli Lilly, Invest Toxicol, Indianapolis, IN USA

Van Vleet, Terry R.
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h-index: 0
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AbbVie Inc, Invest Toxicol & Pathol, Chicago, IL USA Eli Lilly, Invest Toxicol, Indianapolis, IN USA

Mahalingaiah, Prathap Kumar
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h-index: 0
机构:
AbbVie Inc, Invest Toxicol & Pathol, Chicago, IL USA Eli Lilly, Invest Toxicol, Indianapolis, IN USA

Grandhi, Taraka Sai Pavan
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h-index: 0
机构:
GSK, Complex In Vitro Models Grp, Collegeville, PA USA Eli Lilly, Invest Toxicol, Indianapolis, IN USA

Evers, Raymond
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h-index: 0
机构:
Johnson & Johnson, Janssen Pharmaceut, Preclin Sci & Translat Safety, Spring House, PA USA Eli Lilly, Invest Toxicol, Indianapolis, IN USA

Ekert, Jason
论文数: 0 引用数: 0
h-index: 0
机构:
UCB Pharma, Cambridge, MA USA Eli Lilly, Invest Toxicol, Indianapolis, IN USA

Gosset, James R.
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h-index: 0
机构:
Pfizer Inc, Pharmacokinet Dynam & Metab, Med Design, Cambridge, MA USA Eli Lilly, Invest Toxicol, Indianapolis, IN USA

Chacko, Silvi A.
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h-index: 0
机构:
Bristol Myers Squibb Co, Res & Dev, Princeton, NJ USA Eli Lilly, Invest Toxicol, Indianapolis, IN USA

Kopec, Anna K.
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Pfizer Inc, Drug Safety Res & Dev, Groton, CT USA Eli Lilly, Invest Toxicol, Indianapolis, IN USA
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Hardwick, Rhiannon N.
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Kopec, Anna K.
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Liras, Jennifer L.
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ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION,
2022, 39 (02)
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Baran, Szczepan W.
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h-index: 0
机构:
Novartis Inst BioMed Res, Emerging Technol, Cambridge, MA 02139 USA Novartis Inst BioMed Res, Emerging Technol, Cambridge, MA 02139 USA

Brown, Paul C.
论文数: 0 引用数: 0
h-index: 0
机构:
US FDA, Ctr Drug Evaluat & Res, Off New Drugs, Silver Spring, MD USA Novartis Inst BioMed Res, Emerging Technol, Cambridge, MA 02139 USA

Baudy, Andreas R.
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h-index: 0
机构:
Merck & Co Inc, ADME & Discovery Toxicol, Kenilworth, NJ USA Novartis Inst BioMed Res, Emerging Technol, Cambridge, MA 02139 USA

Fitzpatrick, Suzanne C.
论文数: 0 引用数: 0
h-index: 0
机构:
US FDA, Ctr Food Safety & Appl Nutr, Off Ctr Director, College Pk, MD USA Novartis Inst BioMed Res, Emerging Technol, Cambridge, MA 02139 USA

Frantz, Christopher
论文数: 0 引用数: 0
h-index: 0
机构:
Seagen, Translat Sci, Seattle, WA USA Novartis Inst BioMed Res, Emerging Technol, Cambridge, MA 02139 USA

Fullerton, Aaron
论文数: 0 引用数: 0
h-index: 0
机构:
Genentech Inc, Safety Assessment, San Francisco, CA USA Novartis Inst BioMed Res, Emerging Technol, Cambridge, MA 02139 USA

Gan, Jinping
论文数: 0 引用数: 0
h-index: 0
机构:
Bristol Myers Squibb Res & Dev, Pharmaceut Candidate Optimizat, Princeton, NJ USA Novartis Inst BioMed Res, Emerging Technol, Cambridge, MA 02139 USA

Hardwick, Rhiannon N.
论文数: 0 引用数: 0
h-index: 0
机构:
Theravance Biopharma US Inc, Translat Safety Sci, San Francisco, CA USA Novartis Inst BioMed Res, Emerging Technol, Cambridge, MA 02139 USA

Hillgren, Kathleen M.
论文数: 0 引用数: 0
h-index: 0
机构:
Lilly Corp Ctr, Lilly Res Labs, Indianapolis, IN 46285 USA Novartis Inst BioMed Res, Emerging Technol, Cambridge, MA 02139 USA

Kopec, Anna K.
论文数: 0 引用数: 0
h-index: 0
机构:
Pfizer Inc, Drug Safety Res & Dev, Groton, CT 06340 USA Novartis Inst BioMed Res, Emerging Technol, Cambridge, MA 02139 USA

Liras, Jennifer L.
论文数: 0 引用数: 0
h-index: 0
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Pfizer Inc, Pharmacokinet Dynam & Metab, Cambridge, MA USA Novartis Inst BioMed Res, Emerging Technol, Cambridge, MA 02139 USA

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