Phytosteroids from Roots of Psammosilene tunicoides WCWu et CYWu

被引：0

作者：

Wang, Ziliang ^{[1
]}

Li, Hongrui ^{[1
]}

Li, Yuxiao ^{[1
,2
]}

Nie, Kexin ^{[1
]}

Yang, Xiuxia ^{[1
]}

Bai, Xishan ^{[1
]}

Li, Yanhong ^{[1
]}

Huang, Xiangzhong ^{[1
]}

机构：

[1] Yunnan Minzu Univ, Key Lab Chem Ethn Med Resources, State Ethn Affairs Commiss & Minist Educ, Kunming 650504, Yunnan, Peoples R China

[2] Yunnan Plateau Thermal Hlth Ind Innovat Res Inst, Tengchong 679100, Yunnan, Peoples R China

来源：

RECORDS OF NATURAL PRODUCTS | 2024年 / 18卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Psammosilene tunicoides; phytoecdysteroid; nitric oxide inhibition activity; RAW; 264.7; cells;

D O I：

10.25135/rnp.444.2312.2991

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

To explore structurally and pharmacologically interesting secondary metabolites from Psammosilene tunicoides, a crude extract of this plant was investigated, leading to the isolation of a new phytoecdysteroid, furoecdysterone (1) and four known phytosteroid compounds, ecdysterone (2), 22-deoxyecdysterone (3), beta-sitosteryl D-glucoside (4), and beta-sitosterol (5). Their structures were identified based on a detailed analysis of NMR spectra and MS data. Those compounds, except for 2, showed moderate NO inhibition activities on lipopolysaccharide (LPS)-induced release in RAW 264.7 cells.

引用

页码：290 / 295

页数：6