Tissue Factor and COVID-19 Associated Thrombosis

被引:4
作者
Mackman, Nigel [1 ,2 ]
机构
[1] Univ N Carolina, UNC Blood Res Ctr, Dept Med, 116 Manning Dr,8004B Mary Ellen Jones Bldg,CB 7035, Chapel Hill, NC 27599 USA
[2] Univ N Carolina, UNC Blood Res Ctr, Dept Med, Chapel Hill, NC USA
基金
美国国家卫生研究院;
关键词
COVID-19; extracellular vesicles; SARS-CoV-2; thromboplastin; thrombosis; BLOOD MONONUCLEAR-CELLS; HEMOSTASIS; RECEPTOR;
D O I
10.1161/ATVBAHA.123.320144
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Microbial infections activate the innate and adaptive immune systems.1 Pathogen-associated molecular patterns produced by microbes, such as double-stranded RNA, are detected by PRRs (pattern-recognition receptors), such as toll-like receptor 3, and this leads to the expression of interferons and cytokines.(1,2)
引用
收藏
页码:523 / 529
页数:7
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