The relationship between blood vitamin A levels and diabetic retinopathy: a population-based study

被引：5

作者：

Choi, Yu-Jin ^{[1
,2
]}

Kwon, Jin-Woo ^{[1
,2
]}

Jee, Donghyun ^{[1
,2
]}

机构：

[1] Catholic Univ Korea, Coll Med, Dept Ophthalmol & Visual Sci, Seoul, South Korea

[2] St Vincents Hosp, Dept Ophthalmol & Visual Sci, Jungbu Daero 93, Suwon 16247, South Korea

来源：

SCIENTIFIC REPORTS | 2024年 / 14卷 / 01期

关键词：

PREVALENCE; ANGIOGENESIS; FIBROSIS; INFLAMMATION; HSP47; SIRNA; RISK; B2;

D O I：

10.1038/s41598-023-49937-x

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We assessed the relationship between blood vitamin A levels and the risk of diabetic retinopathy. The study was population-based epidemiological study for 11,727 participants aged 40 or older who participated in the Korean National Health and Nutrition Examination Survey. Vitamin A in the blood was classified into quartiles. Diabetic retinopathy was diagnosed by the Early Treatment for Diabetic Retinopathy Study. After adjusting confounding variables such as age, sex, smoking, cholesterol, diabetes prevalence period, glycated hemoglobin levels, and high blood pressure, the odd ratio (OR) of vitamin A at quartile level 4 for diabetic retinopathy was 0.32 (95% confidence interval [CI], 0.14-0.72, P for trend < 0.001). In male, the OR of quartile 3 level vitamin A for diabetic retinopathy was 0.11 (95% CI, 0.01-0.69, P for trend = 0.010). In adults under the age of 60, the OR of vitamin A at quartile level 3 for diabetic retinopathy was 0.10. (95% CI, 0.03-0.29, P for trend < 0.001). Serum vitamin A high levels are associated with low risk of diabetic retinopathy. Particularly, there is a more effective relationship in male and adults under the age of 60.

引用

页数：8

共 46 条

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