Prevalence of Extended-Spectrum Beta-Lactamase Resistance and CTX-M-Group 1 Gene in Escherichia coli from the Water and Sediment of Urbanized Mangrove Ecosystems of Kerala

被引：1

作者：

Sivan, Gopika ^{[1
]}

Sukumaran, Divya P. ^{[1
]}

Ezhuthanikkunnel, Akhil Prakash ^{[1
]}

Abdulla, Mohamed Hatha Ammanamveetil ^{[1
,2
]}

机构：

[1] Cochin Univ Sci & Technol, Sch Marine Sci, Dept Marine Biol Microbiol & Biochem, Kochi, India

[2] Cochin Univ Sci & Technol, Sch Marine Sci, Dept Marine Biol Microbiol & Biochem, Kochi 16, Kochi, India

来源：

MICROBIAL DRUG RESISTANCE | 2023年 / 29卷 / 12期

关键词：

antibiotic resistance; phylogenetic groups; beta-lactam; mangrove; ANTIBIOTIC-RESISTANCE; ANTIMICROBIAL RESISTANCE; FECAL CONTAMINATION; VIRULENCE; BACTERIA; STRAINS; DISSEMINATION; INFECTIONS; PHYLOGENY; DIVERSITY;

D O I：

10.1089/mdr.2023.0089

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The study aimed to determine the prevalence of extended-spectrum beta-lactamase resistance and CTX-M-group 1 gene in Escherichia coli from the water and sediment of three urbanized mangrove ecosystems of Kerala. A total of 119 E. coli isolates were screened for antibiotic susceptibility to 16 antibiotics. According to the phylogenetic analysis of E. coli isolates, nonpathogenic group A and pathogenic group D (29.4% and 23.5%) were the predominant phylotypes found in water samples. The most frequent phylotypes found in sediment samples were nonpathogenic groups A and B1 (27.9% and 26.4%). The highest incidence of antibiotic resistance in E. coli was against cefotaxime and colistin (100%). A significant difference in the prevalence of CTX-M-group 1 gene was observed among E. coli isolates in water samples (p < 0.05). The results indicate a high prevalence of beta-lactamase harboring E. coli in the mangrove ecosystems that can hamper mangrove-dependent aquaculture practices and human health.

引用

页码：582 / 588

页数：7

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