Wilms Tumor

被引：11

作者：

Saltzman, Amanda F. ^{[1
]}

Cost, Nicholas G. ^{[2
,3
]}

Romao, Rodrigo L. P. ^{[4
,5
]}

机构：

[1] Univ Kentucky, Dept Urol, Lexington, KY 40506 USA

[2] Univ Colorado, Sch Med, Dept Surg, Div Urol, 13123 East 16th Ave,B 463, Aurora, CO 80045 USA

[3] Childrens Hosp Colorado, Surg Oncol Program, 13123 East 16th Ave,B 463, Aurora, CO 80045 USA

[4] Dalhousie Univ, IWK Hlth Ctr, Dept Surg, Halifax, NS, Canada

[5] Dalhousie Univ, IWK Hlth Ctr, Dept Urol, Halifax, NS, Canada

来源：

UROLOGIC CLINICS OF NORTH AMERICA | 2023年 / 50卷 / 03期

关键词：

Wilms tumor; Nephroblastoma; Renal tumor; Nephrectomy; Urologic oncology; EXTENSION;

D O I：

10.1016/j.ucl.2023.04.008

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Fortunately, the vast majority of children with WT will enjoy good oncologic outcomes. Therefore, future investigation will focus on improving out-comes for patients at increased risk of relapse and decreasing therapy for patients expected to experience excellent results based on risk stratifi-cation. From a surgical standpoint, for unilateral WT, a complete upfront resection optimizes dis-ease control and allows for ideal biologic risk strat-ification. Specifically, surgical education targeting lymph node sampling, both in terms of location and ideal number of nodes to be sampled, will be a major area of study. In addition, surgical inter-vention can reduce morbidity with the appropriate utilization of post-chemotherapy partial nephrec-tomy for those children with bilateral WT or unilat-eral WT with a predisposition syndrome.

引用

页码：455 / 464

页数：10

共 24 条

[1] Acquired von Willebrand Syndrome and Wilms Tumor: Not Always Benign [J].

Baxter, Patricia A. ;

Nuchtern, Jed G. ;

Guillerman, Robert P. ;

Mahoney, Donald H. ;

Teruya, Jun ;

Chintagumpala, Murali ;

Yee, Donald L. .

PEDIATRIC BLOOD & CANCER, 2009, 52 (03) :392-394

[2] EPIDEMIOLOGY OF WILMS-TUMOR [J].

BRESLOW, N ;

OLSHAN, A ;

BECKWITH, JB ;

GREEN, DM .

MEDICAL AND PEDIATRIC ONCOLOGY, 1993, 21 (03) :172-181

[3] Activity of Vincristine and Irinotecan in Diffuse Anaplastic Wilms Tumor and Therapy Outcomes of Stage II to IV Disease: Results of the Children's Oncology Group AREN0321 Study [J].

Daw, Najat C. ;

Chi, Yueh-Yun ;

Kalapurakal, John A. ;

Kim, Yeonil ;

Hoffer, Fredric A. ;

Geller, James, I ;

Perlman, Elizabeth J. ;

Ehrlich, Peter F. ;

Mullen, Elizabeth A. ;

Warwick, Anne B. ;

Grundy, Paul E. ;

Paulino, Arnold C. ;

Gratias, Eric ;

Ward, Deborah ;

Anderson, James R. ;

Khanna, Geetika ;

Tornwall, Brett ;

Fernandez, Conrad, V ;

Dome, Jeffrey S. .

JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (14) :1558-+

[4] Treatment of stage I anaplastic Wilms' tumour: a report from the Children's Oncology Group AREN0321 study [J].

Daw, Najat C. ;

Chi, Yueh-Yun ;

Kim, Yeonil ;

Mullen, Elizabeth A. ;

Kalapurakal, John A. ;

Tian, Jing ;

Khanna, Geetika ;

Geller, James I. ;

Perlman, Elizabeth J. ;

Ehrlich, Peter F. ;

Warwick, Anne B. ;

Grundy, Paul E. ;

Fernandez, Conrad V. ;

Dome, Jeffrey S. .

EUROPEAN JOURNAL OF CANCER, 2019, 118 :58-66

[5] Augmentation of Therapy for Combined Loss of Heterozygosity 1p and 16q in Favorable Histology Wilms Tumor: A Children's Oncology Group AREN0532 and AREN0533 Study Report [J].

Dix, David B. ;

Fernandez, Conrad V. ;

Chi, Yueh-Yun ;

Mullen, Elizabeth A. ;

Geller, James I. ;

Gratias, Eric J. ;

Khanna, Geetika ;

Kalapurakal, John A. ;

Perlman, Elizabeth J. ;

Seibel, Nita L. ;

Ehrlich, Peter F. ;

Malogolowkin, Marcio ;

Anderson, James ;

Gastier-Foster, Julie ;

Shamberger, Robert C. ;

Kim, Yeonil ;

Grundy, Paul E. ;

Dome, Jeffrey S. .

JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (30) :2769-+

[6] Treatment of Stage IV Favorable Histology Wilms Tumor With Lung Metastases: A Report From the Children's Oncology Group AREN0533 Study [J].

Dix, David B. ;

Seibel, Nita L. ;

Chi, Yueh-Yun ;

Khanna, Geetika ;

Gratias, Eric ;

Anderson, James R. ;

Mullen, Elizabeth A. ;

Geller, James I. ;

Kalapurakal, John A. ;

Paulino, Arnold C. ;

Perlman, Elizabeth J. ;

Ehrlich, Peter F. ;

Malogolowkin, Marcio ;

Gastier-Foster, Julie M. ;

Wagner, Elizabeth ;

Grundy, Paul E. ;

Fernandez, Conrad V. ;

Dome, Jeffrey S. .

JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (16) :1564-+

[7] Children's Oncology Group's 2013 blueprint for research: Renal tumors [J].

Dome, Jeffrey S. ;

Fernandez, Conrad V. ;

Mullen, Elizabeth A. ;

Kalapurakal, John A. ;

Geller, James I. ;

Huff, Vicki ;

Gratias, Eric J. ;

Dix, David B. ;

Ehrlich, Peter F. ;

Khanna, Geetika ;

Malogolowkin, Marcio H. ;

Anderson, James R. ;

Naranjo, Arlene ;

Perlman, Elizabeth J. .

PEDIATRIC BLOOD & CANCER, 2013, 60 (06) :994-1000

[8] Results of the First Prospective Multi-institutional Treatment Study in Children With Bilateral Wilms Tumor (AREN0534) A Report From the Children's Oncology Group [J].

Ehrlich, Peter ;

Chi, Yuen Y. ;

Chintagumpala, Murali M. ;

Hoffer, Fred A. ;

Perlman, Elizabeth J. ;

Kalapurakal, John A. ;

Warwick, Ann ;

Shamberger, Robert C. ;

Khanna, Geetika ;

Hamilton, Tom E. ;

Gow, Ken W. ;

Paulino, Arnold C. ;

Gratias, Eric J. ;

Mullen, Elizabeth A. ;

Geller, James I. ;

Grundy, Paul E. ;

Fernandez, Conrad V. ;

Ritchey, Michael L. ;

Dome, James S. .

ANNALS OF SURGERY, 2017, 266 (03) :470-478

[9]

Ehrlich PF, 2022, ANN SURG ONCOL, V29, P3252, DOI 10.1245/s10434-021-11266-6

[10] Results of treatment for patients with multicentric or bilaterally predisposed unilateral Wilms tumor (AREN0534): A report from the Children's Oncology Group [J].

Ehrlich, Peter F. ;

Chi, Yueh-Yun ;

Chintagumpala, Murali M. ;

Hoffer, Fredric A. ;

Perlman, Elizabeth J. ;

Kalapurakal, John A. ;

Tornwall, Brett ;

Warwick, Anne ;

Shamberger, Robert C. ;

Khanna, Geetika ;

Hamilton, Thomas E. ;

Gow, Kenneth W. ;

Paulino, Arnold C. ;

Gratias, Eric J. ;

Mullen, Elizabeth A. ;

Geller, James I. ;

Grundy, Paul E. ;

Fernandez, Conrad V. ;

Dome, Jeffrey S. .

CANCER, 2020, 126 (15) :3516-3525

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