Metal-Free Direct C3-H Alkylation and Arylation of Quinoxalin-2(1H)-Ones with Inert Alkyl and Aryl Chlorides

被引：8

作者：

Tripathy, Alisha Rani ^{[1
]}

Mishra, Ashutosh ^{[1
]}

Singh, Vesaj ^{[1
]}

Yatham, Veera Reddy ^{[1
]}

机构：

[1] Indian Inst Sci Educ & Res, Sch Chem, Thiruvananthapuram IISER TVM, Thiruvananthapuram 695551, India

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2023年 / 29卷 / 47期

关键词：

alkyl chlorides; halo arenes; organo photocatalyst; quinoxalin-2(1H)-ones; visible-light; LATE-STAGE FUNCTIONALIZATION; PHOTOREDOX CATALYSIS; CHLORINATION; HALIDES; OLEFINS;

D O I：

10.1002/chem.202300774

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the present manuscript, we reported the first visible-light-enabled direct C3-H alkylation/arylation of quinoxalin-2(1H)-ones with unactivated alkyl/aryl chlorides under metal-free conditions. A wide range of unactivated alkyl and aryl chlorides containing different functionalities are coupled with a variety of quinoxalin-2(1H)-one derivatives under mild reaction conditions to afford the C3-alkyl/aryl substituted quinoxalin-2(1H)-ones in moderate to good yields.

引用

页数：6

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