Review on Different Vesicular Drug Delivery Systems (VDDSs) and Their Applications

被引:24
作者
Alenzi, Asma M. [1 ]
Albalawi, Sana A. [1 ]
Alghamdi, Shatha G. [1 ]
Albalawi, Rawan F. [1 ]
Albalawi, Hadeel S. [1 ]
Qushawy, Mona [2 ,3 ]
机构
[1] Univ Tabuk, Fac Pharm, Pharm Program D, Tabuk, Saudi Arabia
[2] Univ Tabuk, Fac Pharm, Dept Pharmaceut, Tabuk 71491, Saudi Arabia
[3] Sinai Univ, Fac Pharm, Dept Pharmaceut, Alarish 45511, N Sinai, Egypt
关键词
Drug delivery; niosomes; liposomes; bioavailability; drug targeting; colloidal dispersion; TRANSDERMAL DELIVERY; SYNERGISTIC PENETRATION; ORAL IMMUNIZATION; TOPICAL DELIVERY; IN-VITRO; LIPOSOMES; CUBOSOMES; NIOSOMES; CARRIER; PHARMACOSOMES;
D O I
10.2174/1872210516666220228150624
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Background: Colloidal dispersions, also known as vesicular drug delivery systems (VDDSs), are highly ordered assemblies composed of one or more concentric bilayers formed by the self-assembly of amphiphilic building blocks in the presence of water. Objective: VDDSs are important to target the entrapped drugs at specific sites inside the body, control the drug release, enhance the drug bioavailability, and reduce undesired side effects. Methods: There are different types of VDDSs suitable for the entrapment of both hydrophilic and lipophilic drugs. According to the patent composition, VDDSs are classified into lipid-based and non-lipid-based VDDSs. Results: There are different types of VDDSs which include liposomes, ethosomes, transferosomes, ufasomes, colloidosomes, cubosomes, niosomes, bilosomes, aquasomes, etc. Conclusion: This review article aims to address the different types of VDDSs, their advantages and disadvantages, and their therapeutic applications.
引用
收藏
页码:18 / 32
页数:15
相关论文
共 139 条
[41]   Transferosomes as nanocarriers for drugs across the skin: Quality by design from lab to industrial scale [J].
Fernandez-Garcia, Raquel ;
Lalatsa, Aikaterini ;
Statts, Larry ;
Bolas-Fernandez, Francisco ;
Paloma Ballesteros, M. ;
Serrano, Dolores R. .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2020, 573
[42]  
Gaballa S.A., 2020, J. Adv. Biomed. Pharm. Sci, V3, P1, DOI [10.21608/jabps.2019.16887.1057, DOI 10.21608/JABPS.2019.16887.1057]
[43]   Cubosomes: An overview [J].
Garg, Gopal ;
Saraf, Shailendra ;
Saraf, Swarnlata .
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2007, 30 (02) :350-353
[44]   UFASOMES ARE STABLE PARTICLES SURROUNDED BY UNSATURATED FATTY-ACID MEMBRANES [J].
GEBICKI, JM ;
HICKS, M .
NATURE, 1973, 243 (5404) :232-234
[45]   PREPARATION AND PROPERTIES OF VESICLES ENCLOSED BY FATTY-ACID MEMBRANES [J].
GEBICKI, JM ;
HICKS, M .
CHEMISTRY AND PHYSICS OF LIPIDS, 1976, 16 (02) :142-160
[46]  
Godin Biana, 2005, Current Drug Delivery, V2, P269, DOI 10.2174/1567201054367931
[47]   CHEMICAL-STABILITY OF LIPOSOMES - IMPLICATIONS FOR THEIR PHYSICAL STABILITY [J].
GRIT, M ;
CROMMELIN, JA .
CHEMISTRY AND PHYSICS OF LIPIDS, 1993, 64 (1-3) :3-18
[48]   Antileishmanial activity and immune modulatory effects of benzoxonium chloride and its entrapped forms in niosome on Leishmania tropica [J].
Hakimi Parizi M. ;
Pardakhty A. ;
sharifi I. ;
Farajzadeh S. ;
Daie Parizi M.H. ;
Sharifi H. ;
Keyhani A.R. ;
Mostafavi M. ;
Bamorovat M. ;
Ghaffari D. .
Journal of Parasitic Diseases, 2019, 43 (3) :406-415
[49]   Gene therapy and DNA delivery systems [J].
Ibraheem, D. ;
Elaissari, A. ;
Fessi, H. .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2014, 459 (1-2) :70-83
[50]   Sugar-based novel niosomal nanocarrier system for enhanced oral bioavailability of levofloxacin [J].
Imran, Muhammad ;
Shah, Muhammad Raza ;
Ullah, Farhat ;
Ullah, Shafi ;
Elhissi, Abdelbary M. A. ;
Nawaz, Waqas ;
Ahmad, Farid ;
Sadiq, Abdul ;
Ali, Imdad .
DRUG DELIVERY, 2016, 23 (09) :3653-3664