Review on Different Vesicular Drug Delivery Systems (VDDSs) and Their Applications

被引：24
作者：
Alenzi, Asma M. [1 ]
Albalawi, Sana A. [1 ]
Alghamdi, Shatha G. [1 ]
Albalawi, Rawan F. [1 ]
Albalawi, Hadeel S. [1 ]
Qushawy, Mona [2 ,3 ]
机构：
[1] Univ Tabuk, Fac Pharm, Pharm Program D, Tabuk, Saudi Arabia
[2] Univ Tabuk, Fac Pharm, Dept Pharmaceut, Tabuk 71491, Saudi Arabia
[3] Sinai Univ, Fac Pharm, Dept Pharmaceut, Alarish 45511, N Sinai, Egypt
来源：
RECENT PATENTS ON NANOTECHNOLOGY | 2023年 / 17卷 / 01期
关键词：
Drug delivery; niosomes; liposomes; bioavailability; drug targeting; colloidal dispersion; TRANSDERMAL DELIVERY; SYNERGISTIC PENETRATION; ORAL IMMUNIZATION; TOPICAL DELIVERY; IN-VITRO; LIPOSOMES; CUBOSOMES; NIOSOMES; CARRIER; PHARMACOSOMES;
D O I：
10.2174/1872210516666220228150624
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Background: Colloidal dispersions, also known as vesicular drug delivery systems (VDDSs), are highly ordered assemblies composed of one or more concentric bilayers formed by the self-assembly of amphiphilic building blocks in the presence of water. Objective: VDDSs are important to target the entrapped drugs at specific sites inside the body, control the drug release, enhance the drug bioavailability, and reduce undesired side effects. Methods: There are different types of VDDSs suitable for the entrapment of both hydrophilic and lipophilic drugs. According to the patent composition, VDDSs are classified into lipid-based and non-lipid-based VDDSs. Results: There are different types of VDDSs which include liposomes, ethosomes, transferosomes, ufasomes, colloidosomes, cubosomes, niosomes, bilosomes, aquasomes, etc. Conclusion: This review article aims to address the different types of VDDSs, their advantages and disadvantages, and their therapeutic applications.
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页码：18 / 32
页数：15
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