Review on Different Vesicular Drug Delivery Systems (VDDSs) and Their Applications

被引：24
作者：
Alenzi, Asma M. [1 ]
Albalawi, Sana A. [1 ]
Alghamdi, Shatha G. [1 ]
Albalawi, Rawan F. [1 ]
Albalawi, Hadeel S. [1 ]
Qushawy, Mona [2 ,3 ]
机构：
[1] Univ Tabuk, Fac Pharm, Pharm Program D, Tabuk, Saudi Arabia
[2] Univ Tabuk, Fac Pharm, Dept Pharmaceut, Tabuk 71491, Saudi Arabia
[3] Sinai Univ, Fac Pharm, Dept Pharmaceut, Alarish 45511, N Sinai, Egypt
来源：
RECENT PATENTS ON NANOTECHNOLOGY | 2023年 / 17卷 / 01期
关键词：
Drug delivery; niosomes; liposomes; bioavailability; drug targeting; colloidal dispersion; TRANSDERMAL DELIVERY; SYNERGISTIC PENETRATION; ORAL IMMUNIZATION; TOPICAL DELIVERY; IN-VITRO; LIPOSOMES; CUBOSOMES; NIOSOMES; CARRIER; PHARMACOSOMES;
D O I：
10.2174/1872210516666220228150624
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Background: Colloidal dispersions, also known as vesicular drug delivery systems (VDDSs), are highly ordered assemblies composed of one or more concentric bilayers formed by the self-assembly of amphiphilic building blocks in the presence of water. Objective: VDDSs are important to target the entrapped drugs at specific sites inside the body, control the drug release, enhance the drug bioavailability, and reduce undesired side effects. Methods: There are different types of VDDSs suitable for the entrapment of both hydrophilic and lipophilic drugs. According to the patent composition, VDDSs are classified into lipid-based and non-lipid-based VDDSs. Results: There are different types of VDDSs which include liposomes, ethosomes, transferosomes, ufasomes, colloidosomes, cubosomes, niosomes, bilosomes, aquasomes, etc. Conclusion: This review article aims to address the different types of VDDSs, their advantages and disadvantages, and their therapeutic applications.
引用
收藏
页码：18 / 32
页数：15
相关论文
共 139 条
[1]   Formulation and Characterization of Cinnarizine Targeted Aural Transfersomal Gel for Vertigo Treatment: A Pharmacokinetic Study on Rabbits [J].
Abdelmonem, Rehab ;
Hamed, Raghda Rabe ;
Abdelhalim, Sally A. ;
ElMiligi, Mohamed F. ;
El-Nabarawi, Mohamed A. .
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2020, 15 :6211-6223
[2]   Novel in situ gelling vaginal sponges of sildenafil citrate-based cubosomes for uterine targeting [J].
Aboud, Heba M. ;
Hassan, Amira H. ;
Ali, Adel A. ;
Abdel-Razik, Abdel-Razik H. .
DRUG DELIVERY, 2018, 25 (01) :1328-1339
[3]   Potential Use of Niosomal Hydrogel as an Ocular Delivery System for Atenolol [J].
Abu Hashim, Irhan Ibrahim ;
El-dahan, Marwa Salah ;
Yusif, Rehab Mohammed ;
Abd-ElGawad, Abd-ElGawad Helmy ;
Arima, Hidetoshi .
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2014, 37 (04) :541-551
[4]  
Aggarwal D., 2016, Int. J. Pharm. Med. Res, V4, P354
[5]   In vitro and in vivo evaluation of cubosomal in situ nasal gel containing resveratrol for brain targeting [J].
Ahirrao, Mayuri ;
Shrotriya, Shilpa .
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2017, 43 (10) :1686-1693
[6]  
Ahmed AMS., 2013, INT J DRUG DEV RES, V5, P121
[7]   Testosterone ethosomes for enhanced transdermal delivery [J].
Ainbinder, D ;
Touitou, E .
DRUG DELIVERY, 2005, 12 (05) :297-303
[8]   Liposome: classification, preparation, and applications [J].
Akbarzadeh, Abolfazl ;
Rezaei-Sadabady, Rogaie ;
Davaran, Soodabeh ;
Joo, Sang Woo ;
Zarghami, Nosratollah ;
Hanifehpour, Younes ;
Samiei, Mohammad ;
Kouhi, Mohammad ;
Nejati-Koshki, Kazem .
NANOSCALE RESEARCH LETTERS, 2013, 8
[9]   Investigating the potential of employing bilosomes as a novel vesicular carrier for transdermal delivery of tenoxicam [J].
Al-mahallawi, Abdulaziz M. ;
Abdelbary, Aly A. ;
Aburahma, Mona H. .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2015, 485 (1-2) :329-340
[10]   Comparative study of transfersomes, liposomes, and niosomes for topical delivery of 5-fluorouracil to skin cancer cells: preparation, characterization, in-vitro release, and cytotoxicity analysis [J].
Alvi, Iqrar Ali ;
Madan, Jitender ;
Kaushik, Dinesh ;
Sardana, Satish ;
Pandey, Ravi Shankar ;
Ali, Asgar .
ANTI-CANCER DRUGS, 2011, 22 (08) :774-782
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