Role of 68Ga-FAPI-04 PET/CT in the Initial Staging of Esophageal Cancer

被引：7

作者：

Liu, Huipan ^{[1
,2
,3
,4
]}

Yang, Xiao ^{[5
]}

You, Zhouxiang ^{[6
]}

Hu, Zhi ^{[6
]}

Chen, Yue ^{[1
,2
,3
,4
]}

机构：

[1] Southwest Med Univ, Affiliated Hosp, Dept Nucl Med, Luzhou, Peoples R China

[2] Southwest Med Univ, Affiliated Hosp, Nucl Med & Mol Imaging Key Lab Sichuan Prov, Luzhou, Peoples R China

[3] Southwest Med Univ, Affiliated Hosp, Academician Expert Workstat Sichuan Prov, Luzhou, Peoples R China

[4] Southwest Med Univ, Inst Nucl Med, Luzhou, Peoples R China

[5] Yibin 2 Peoples Hosp, Dept Nucl Med, Yibin, Peoples R China

[6] Southwest Med Univ, Affiliated Hosp, Dept Thorac Surg, Luzhou, Peoples R China

来源：

NUKLEARMEDIZIN-NUCLEAR MEDICINE | 2023年 / 62卷 / 01期

关键词：

68Ga-FAPI-04; PET; CT; esophageal carcinoma; lymph node metastasis; initial staging; PATIENT;

D O I：

10.1055/a-1984-8044

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Aim To investigate the clinical value of 68Ga-FAPI-04 PET/CT for initial staging of esophageal cancer. Methods A total of 44 newly diagnosed patients with esophageal cancer were included in the analysis on the basis of postoperative pathology or clinical and radiologic follow-up.Results All primary lesions showed increased 68Ga-FAPI-04 uptake, with an SUVmax of 14.92 +/- 6.91. A total of 561 lymph nodes were verified by surgery (507) or clinical and radiologic follow-up (54), of which 92 lymph nodes were diagnosed as showing metastases. Seventy-five lymph nodes with metastases showed positive findings on 68Ga-FAPI-04, with a diameter of about 1.06 +/- 0.53 cm and SUVmax of 8.10 +/- 4.71. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value for lymph node metastasis detection were 81.5%, 99.3%, 96.6%, 96.2 %, and 96.5%, respectively.Conclusion 68Ga-FAPI-04 PET/CT showed good diagnostic performance in detecting lymph node metastases of esophageal cancer.

引用

页码：38 / 44

页数：7

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