Boosting light absorption of a therapeutic microcapsule by means of auxiliary solid nanoparticles

被引:3
作者
Geints, Yu. E. [1 ]
Panina, E. K. [1 ]
机构
[1] VE Zuev Inst Atmospher Opt, 1 Acad Zuev Sq, Tomsk 634021, Russia
基金
俄罗斯科学基金会;
关键词
Polycomposite microcapsule; Optical opening; Light absorption; Nanoparticles; Photonic nanojet; Field enhancement; PHOTONIC-NANOJETS; RELEASE; ENHANCEMENT;
D O I
10.1016/j.optcom.2023.129444
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Multilayer microparticles with a liquid core and a polycomposite light-absorbing shell are important com-ponents of modern bio-and medical technologies, in particular, serving as transport microcontainers in the targeted delivery of therapeutic nanodoses to the desired region of the biological tissues. For reliably opening the microcapsule shell by an optical radiation and releasing the payload, it is necessary to dramatically increase the light absorption of such a microcontainer. To this end, we propose surrounding the microcapsule with specially added auxiliary nanoparticles, which can accumulate optical energy near its surface and direct a concentrated photonic flux to the target microcapsule thus leading to its booster heating. Using numerical finite-difference time-domain (FDTD) calculations, we simulate and examine the absorption dynamics of the near-infrared optical radiation in a spherical microcapsule surrounded by solid nanoparticles of different optical properties (metal, biocompatible dielectric). We show that due to light scattering on nanoparticles, the optical field superlocalization in the "hot regions" on the microcapsule surface occurs. Up to the three-fold light absorption enhancement can be achieved due to the addition of nanoparticles.
引用
收藏
页数:8
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