A Post-Pandemic Enigma: The Cardiovascular Impact of Post-Acute Sequelae of SARS-CoV-2

被引：5
作者：
Singh, Tamanna K. [1 ,5 ,6 ]
Zidar, David A. [6 ,7 ]
McCrae, Keith [2 ,5 ,6 ]
Highland, Kristin B. [4 ,5 ,6 ]
Englund, Kristin [3 ,5 ,6 ]
Cameron, Scott J. [1 ,5 ,6 ]
Chung, Mina K. [5 ,6 ]
机构：
[1] Cleveland Clin, Heart Vasc & Thorac Inst, Cleveland, OH 44195 USA
[2] Cleveland Clin, Hematol & Med Oncol, Cleveland, OH USA
[3] Cleveland Clin, Infect Dis, Cleveland, OH USA
[4] Cleveland Clin, Pulm Med, Cleveland, OH USA
[5] Cleveland Clin Lerner Coll Med, Cleveland, OH USA
[6] Case Western Reserve Univ, Sch Med, Cleveland, OH USA
[7] Louise Stokes Cleveland Vet Affairs Med Ctr, Dept Cardiovasc Med, Cleveland, OH USA
来源：
CIRCULATION RESEARCH | 2023年 / 132卷 / 10期
关键词：
COVID-19; infections; pandemics; SARS-CoV-2; survivors; ACUTE MYOCARDIAL-INFARCTION; CORONAVIRUS DISEASE 2019; ORTHOSTATIC TACHYCARDIA; COVID-19; PATIENTS; HOSPITALIZED-PATIENTS; AUTOPSY FINDINGS; FATIGUE-SYNDROME; UNITED-STATES; HIV-INFECTION; DIAGNOSIS;
D O I：
10.1161/CIRCRESAHA.122.322228
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
COVID-19 has become the first modern-day pandemic of historic proportion, affecting >600 million individuals worldwide and causing >6.5 million deaths. While acute infection has had devastating consequences, postacute sequelae of SARS-CoV-2 infection appears to be a pandemic of its own, impacting up to one-third of survivors and often causing symptoms suggestive of cardiovascular phenomena. This review will highlight the suspected pathophysiology of postacute sequelae of SARS-CoV-2, its influence on the cardiovascular system, and potential treatment strategies.
引用
收藏
页码：1358 / 1373
页数：16
相关论文
共 151 条
[1]   Post-COVID syndrome. A case series and comprehensive review [J].
Anaya, Juan-Manuel ;
Rojas, Manuel ;
Salinas, Martha L. ;
Rodriguez, Yhojan ;
Roa, Geraldine ;
Lozano, Marcela ;
Rodriguez-Jimenez, Monica ;
Montoya, Norma ;
Zapata, Elizabeth ;
Monsalve, Diana M. ;
Acosta-Ampudia, Yeny ;
Ramirez-Santana, Carolina .
AUTOIMMUNITY REVIEWS, 2021, 20 (11)
[2]   Myocardial Involvement After Hospitalization for COVID-19 Complicated by Troponin Elevation: A Prospective, Multicenter, Observational Study [J].
Artico, Jessica ;
Shiwani, Hunain ;
Moon, James C. ;
Gorecka, Miroslawa ;
McCann, Gerry P. ;
Roditi, Giles ;
Morrow, Andrew ;
Mangion, Kenneth ;
Lukaschuk, Elena ;
Shanmuganathan, Mayooran ;
Miller, Christopher A. ;
Chiribiri, Amedeo ;
Prasad, Sanjay K. ;
Adam, Robert D. ;
Singh, Trisha ;
Bucciarelli-Ducci, Chiara ;
Dawson, Dana ;
Knight, Daniel ;
Fontana, Marianna ;
Manisty, Charlotte ;
Treibel, Thomas A. ;
Levelt, Eylem ;
Arnold, Ranjit ;
Macfarlane, Peter W. ;
Young, Robin ;
McConnachie, Alex ;
Neubauer, Stefan ;
Piechnik, Stefan K. ;
Davies, Rhodri H. ;
Ferreira, Vanessa M. ;
Dweck, Marc R. ;
Berry, Colin ;
Greenwood, John P. .
CIRCULATION, 2023, 147 (05) :364-374
[3]   Long COVID: mechanisms, risk factors and recovery [J].
Astin, Ronan ;
Banerjee, Amitava ;
Baker, Mark R. ;
Dani, Melanie ;
Ford, Elizabeth ;
Hull, James H. ;
Lim, Phang Boon ;
McNarry, Melitta ;
Morten, Karl ;
O'Sullivan, Oliver ;
Pretorius, Etheresia ;
Raman, Betty ;
Soteropoulos, Demetris S. ;
Taquet, Maxime ;
Hall, Catherine N. .
EXPERIMENTAL PHYSIOLOGY, 2023, 108 (01) :12-27
[4]   Trajectory of long covid symptoms after covid-19 vaccination: community based cohort study [J].
Ayoubkhani, Daniel ;
Bermingham, Charlotte ;
Pouwels, Koen B. ;
Glickman, Myer ;
Nafilyan, Vahe ;
Zaccardi, Francesco ;
Khunti, Kamlesh ;
Alwan, Nisreen A. ;
Walker, A. Sarah .
BMJ-BRITISH MEDICAL JOURNAL, 2022, 377
[5]   ESC guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic: part 2-care pathways, treatment, and follow-up [J].
Baigent, Colin ;
Windecker, Stephan ;
Andreini, Daniele ;
Arbelo, Elena ;
Barbato, Emanuele ;
Bartorelli, Antonio L. ;
Baumbach, Andreas ;
Behr, Elijah R. ;
Berti, Sergio ;
Bueno, Hector ;
Capodanno, Davide ;
Cappato, Riccardo ;
Chieffo, Alaide ;
Collet, Jean-Philippe ;
Cuisset, Thomas ;
de Simone, Giovanni ;
Delgado, Victoria ;
Dendale, Paul ;
Dudek, Dariusz ;
Edvardsen, Thor ;
Elvan, Arif ;
Gonzalez-Juanatey, Jose R. ;
Gori, Mauro ;
Grobbee, Diederick ;
Guzik, Tomasz J. ;
Halvorsen, Sigrun ;
Haude, Michael ;
Heidbuchel, Hein ;
Hindricks, Gerhard ;
Ibanez, Borja ;
Karam, Nicole ;
Katus, Hugo ;
Klok, Fredrikus A. ;
Konstantinides, Stavros, V ;
Landmesser, Ulf ;
Leclercq, Christophe ;
Leonardi, Sergio ;
Lettino, Maddalena ;
Marenzi, Giancarlo ;
Mauri, Josepa ;
Metra, Marco ;
Morici, Nuccia ;
Mueller, Christian ;
Petronio, Anna Sonia ;
Polovina, Marija M. ;
Potpara, Tatjana ;
Praz, Fabien ;
Prendergast, Bernard ;
Prescott, Eva ;
Price, Susanna .
CARDIOVASCULAR RESEARCH, 2022, 118 (07) :1618-1666
[6]   ST-Segment Elevation in Patients with Covid-19-A Case Series [J].
Bangalore, Sripal ;
Sharma, Atul ;
Slotwiner, Alexander .
NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382 (25) :2478-2480
[7]   Discrete SARS-CoV-2 antibody titers track with functional humoral stability [J].
Bartsch, Yannic C. ;
Fischinger, Stephanie ;
Siddiqui, Sameed M. ;
Chen, Zhilin ;
Yu, Jingyou ;
Gebre, Makda ;
Atyeo, Caroline ;
Gorman, Matthew J. ;
Zhu, Alex Lee ;
Kang, Jaewon ;
Burke, John S. ;
Slein, Matthew ;
Gluck, Matthew J. ;
Beger, Samuel ;
Hu, Yiyuan ;
Rhee, Justin ;
Petersen, Eric ;
Mormann, Benjamin ;
Aubin, Michael de St ;
Hasdianda, Mohammad A. ;
Jambaulikar, Guruprasad ;
Boyer, Edward W. ;
Sabeti, Pardis C. ;
Barouch, Dan H. ;
Julg, Boris D. ;
Musk, Elon R. ;
Menon, Anil S. ;
Lauffenburger, Douglas A. ;
Nilles, Eric J. ;
Alter, Galit .
NATURE COMMUNICATIONS, 2021, 12 (01)
[8]   Pathological features of COVID-19-associated myocardial injury: a multicentre cardiovascular pathology study [J].
Basso, Cristina ;
Leone, Ornella ;
Rizzo, Stefania ;
De Gaspari, Monica ;
van der Wal, Allard C. ;
Aubry, Marie-Christine ;
Bois, Melanie C. ;
Lin, Peter T. ;
Maleszewski, Joseph J. ;
Stone, James R. .
EUROPEAN HEART JOURNAL, 2020, 41 (39) :3827-3835
[9]   MITOCHONDRIAL ABNORMALITIES IN THE POSTVIRAL FATIGUE SYNDROME [J].
BEHAN, WMH ;
MORE, IAR ;
BEHAN, PO .
ACTA NEUROPATHOLOGICA, 1991, 83 (01) :61-65
[10]   The proinflammatory CD14+CD16+DR++ monocytes are a major source of TNF [J].
Belge, KU ;
Dayyani, F ;
Horelt, A ;
Siedlar, M ;
Frankenberger, M ;
Frankenberger, B ;
Espevik, T ;
Ziegler-Heitbrock, L .
JOURNAL OF IMMUNOLOGY, 2002, 168 (07) :3536-3542
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