Role of intestinal probiotics in the modulation of lipid metabolism: implications for therapeutic treatments

被引:26
作者
Song, Xiaoran [1 ,2 ]
Liu, Yanan [2 ]
Zhang, Xin [2 ]
Weng, Peifang [2 ]
Zhang, Ruilin [1 ,3 ]
Wu, Zufang [2 ]
机构
[1] Shenzhen Univ Gen Hosp, Cent Lab, Shenzhen 518055, Peoples R China
[2] Ningbo Univ, Coll Food & Pharmaceut Sci, Ningbo 315800, Peoples R China
[3] Shenzhen Univ, Sch Med, Dept Biomed Engn, Guangdong Key Lab Biomed Measurements & Ultrasound, Shenzhen 518060, Peoples R China
关键词
Probiotics; Lipid metabolism; Intestinal flora; CHAIN FATTY-ACIDS; DIET-INDUCED OBESITY; GUT MICROBIOTA; BODY-WEIGHT; FOOD-INTAKE; MICE; SUPPLEMENTATION; CHOLESTEROL; PROPIONATE; SECRETION;
D O I
10.1016/j.fshw.2023.02.005
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Currently, accumulating pieces of evidence indicate that probiotics, living in the gastrointestinal tract, play an important role in regulating host metabolism. As a tool, probiotics have great potential for treating lipid metabolism diseases. However, the relationship between probiotics and abnormal lipid metabolism is still unclear, and the mechanism of action has been become a focus of microbiome research. Therefore, taking intestinal probiotics as the starting point, this article combs the relationship between probiotics and lipid metabolism. Moreover, we discuss the underlying mechanisms of intestinal probiotics regulating lipid metabolism and summarize the therapeutic strategies for abnormal lipids metabolism. This article provides a reference for the further utilization of probiotics in the field of functional foods (food industry). Meanwhile, it will benefit the clinical diagnosis and treatment of lipid metabolism diseases. (c) 2023 Beijing Academy of Food Sciences. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
引用
收藏
页码:1439 / 1449
页数:11
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