Nuclear genome influences mitochondrial DNA

被引:0
作者
Ertl, Henry
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D O I
10.1038/s41576-023-00667
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
A paper in Nature finds that nuclear genetic variation can influence heteroplasmy and the human mitochondrial genome.
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  • [1] Nuclear genetic control of mtDNA copy number and heteroplasmy in humans
    Gupta, Rahul
    Kanai, Masahiro
    Durham, Timothy J.
    Tsuo, Kristin
    McCoy, Jason G.
    Kotrys, Anna V.
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    Mootha, Vamsi K.
    [J]. NATURE, 2023, 620 (7975) : 839 - 848
  • [2] Extreme heterogeneity of human mitochondrial DNA from organelles to populations
    Stewart, James B.
    Chinnery, Patrick F.
    [J]. NATURE REVIEWS GENETICS, 2021, 22 (02) : 106 - 118