The Effect of Upper Abdominal Surgery on Complication Profile in Ovarian Cancer

被引:0
作者
Kiran, Gurkan [1 ]
Tanoglu, Fatma Basak [1 ,3 ]
Cetin, Caglar [1 ]
Pasin, Ozge [2 ]
机构
[1] Bezmialem Univ, Fac Med, Dept Obstet & Gynecol, Istanbul, Turkiye
[2] Bezmialem Univ, Fac Med, Dept Biostat, Istanbul, Turkiye
[3] Bezmialem Vakif Univ Hosp, Iskender Pasa Mh Adnan Menderes Bulvari, TR-34093 Istanbul, Turkiye
关键词
ovarian cancer; cytoreductive surgery; postoperative complication; postoperative morbidity; ADVANCED-STAGE OVARIAN; CYTOREDUCTIVE SURGERY; SURVIVAL; MANAGEMENT; IMPACT; CARCINOMA; RESECTION;
D O I
10.21614/chirurgia.2023.v.118.i.3.p.281
中图分类号
R61 [外科手术学];
学科分类号
摘要
Introduction: Due to the superficial peritoneal spread of ovarian cancer, upper abdominal surgical procedures are often required to achieve optimal surgical cytoreduction. This study compares the mortality and morbidity rates of patients undergoing upper and lower abdominal cytoreductive surgery in our institution.Material and Methods: Patients who underwent cytoreductive surgery for ovarian malignancies from 2014 to 2020 were retrospectively identified from an institutional database. Upper abdominal cytoreduction was defined anatomically as debulking of disease proximal to the ligament of Treitz. Perioperative and postoperative outcomes were analyzed.Results: A total of 148 operations were performed. A single gynecologic oncologist performed all procedures. When all cytoreductive procedures were evaluated, diaphragm injury, blood transfu-sion, hospital stay, atelectasis, pneumonia, effusion, wound infection and need for intensive care were found to be statistically significantly higher in patients who underwent upper abdominal surgery compared to patients in the lower abdominal surgery group (p=0.001, p=0.017, p=0.002, p=0.045, p=0.006, p=0.005, respectively). Conclusion: In patients scheduled for cytoreductive surgery with the diagnosis of ovarian cancer, upper abdominal surgery is a viable procedure, although it carries a higher risk of complications compared to lower abdominal surgery alone. Upper abdominal surgery in advanced ovarian cancer can be applied to patients with an acceptable complication profile when the possible survival advantage is considered.
引用
收藏
页码:281 / 290
页数:10
相关论文
共 30 条
  • [1] Ultra-radical (extensive) surgery versus standard surgery for the primary cytoreduction of advanced epithelial ovarian cancer
    Ang, C.
    Chan, K. K. L.
    Bryant, A.
    Naik, R.
    Dickinson, H. O.
    [J]. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2011, (04):
  • [2] Does Extensive Upper Abdomen Surgery During Primary Cytoreduction Impact on Long-term Quality of Life?
    Angioli, Roberto
    Plotti, Francesco
    Aloisi, Alessia
    Capriglione, Stella
    Terranova, Corrado
    Ricciardi, Roberto
    Montera, Roberto
    Zullo, Marzio Angelo
    Rasi, Virginia
    Benedetti-Panici, Pierluigi
    [J]. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2013, 23 (03) : 442 - 447
  • [3] Association of Diaphragmatic Surgery as Part of Cytoreductive Effort in Advanced Stage Ovarian Cancer
    Bacalbasa, Nicolae
    Balescu, Irina
    Balalau, Cristian
    Ionescu, Olivia
    Stoica, Claudia
    [J]. IN VIVO, 2018, 32 (02): : 431 - 436
  • [4] Survival effect of maximal cytoreductive surgery for advanced ovarian carcinoma during the platinum era: A meta-analysis
    Bristow, RE
    Tomacruz, RS
    Armstrong, DK
    Trimble, EL
    Montz, FJ
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2002, 20 (05) : 1248 - 1259
  • [5] Complications of radical surgery for advanced ovarian cancer
    Chereau, E.
    Ballester, M.
    Lesieur, B.
    Selle, F.
    Coutant, C.
    Rouzier, R.
    Darai, E.
    [J]. GYNECOLOGIE OBSTETRIQUE & FERTILITE, 2011, 39 (01): : 21 - 27
  • [6] The incidence of major complications after the performance of extensive upper abdominal surgical procedures during primary cytoreduction of advanced ovarian, tubal, and peritoneal carcinomas
    Chi, Dennis S.
    Zivanovic, Oliver
    Levinson, Kimberly L.
    Kolev, Valentin
    Huh, Jae
    Dottino, Joseph
    Gardner, Ginger J.
    Leitao, Mario M., Jr.
    Levine, Douglas A.
    Sonoda, Yukio
    Abu-Rustum, Nadeem R.
    Brown, Carol L.
    Barakat, Richard R.
    [J]. GYNECOLOGIC ONCOLOGY, 2010, 119 (01) : 38 - 42
  • [7] Improved progression-free and overall survival in advanced ovarian cancer as a result of a change in surgical paradigm
    Chi, Dennis S.
    Eisenhauer, Eric L.
    Zivanovic, Oliver
    Sonoda, Yukio
    Abu-Rustum, Nadeem R.
    Levine, Douglas A.
    Guile, Matthew W.
    Bristow, Robert E.
    Aghajanian, Carol
    Barakat, Richard R.
    [J]. GYNECOLOGIC ONCOLOGY, 2009, 114 (01) : 26 - 31
  • [8] Diaphragm resection for ovarian cancer: technique and short-term complications
    Cliby, W
    Dowdy, S
    Feitoza, SS
    Gostout, BS
    Podratz, KC
    [J]. GYNECOLOGIC ONCOLOGY, 2004, 94 (03) : 655 - 660
  • [9] SURGERY IN THE TREATMENT OF ACUTE PANCREATITIS - MINIMAL ACCESS PANCREATIC NECROSECTOMY
    Connor, S.
    Raraty, M. G. T.
    Howes, N.
    Evans, J.
    Ghaneh, P.
    Sutton, R.
    Neoptolemos, J. P.
    [J]. SCANDINAVIAN JOURNAL OF SURGERY, 2005, 94 (02) : 135 - 142
  • [10] Distant metastases in ovarian carcinoma
    Cormio, G
    Rossi, C
    Cazzolla, A
    Resta, L
    Loverro, G
    Greco, P
    Selvaggi, L
    [J]. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2003, 13 (02) : 125 - 129