A Review of the Benefits 3D Printing Brings to Patients with Neurological Diseases

被引:11
作者
Gander, Christine [1 ]
Shi, Kejing [2 ]
Nokhodchi, Ali [1 ,3 ]
Lam, Matthew [1 ,4 ]
机构
[1] Univ Sussex, Sch Life Sci, Pharmaceut Res Lab, Arundel Bldg, Brighton BN1 9QJ, England
[2] Univ East London, Sch Hlth Sport & Biosci, Med Res Grp, Water Lane, London E15 4LZ, England
[3] Lupin Pharmaceut Res Ctr, 4006 NW 124th Ave, Coral Springs, FL 33065 USA
[4] London Metropolitan Univ, Sch Human Sci, Dept Chem & Pharmaceut Sci, 166-220 Holloway Rd, London N7 8DB, England
关键词
3D drug printing; personalized medicine; neurosurgery; bioprinting; implants; PARKINSONS-DISEASE; PHARMACOKINETICS; POLYPHARMACY; THERAPY; RELEASE;
D O I
10.3390/pharmaceutics15030892
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
This interdisciplinary review focuses on how flexible three-dimensional printing (3DP) technology can aid patients with neurological diseases. It covers a wide variety of current and possible applications ranging from neurosurgery to customizable polypill along with a brief description of the various 3DP techniques. The article goes into detail about how 3DP technology can aid delicate neurosurgical planning and its consequent outcome for patients. It also covers areas such as how the 3DP model can be utilized in patient counseling along with designing specific implants involved in cranioplasty and customization of a specialized instrument such as 3DP optogenetic probes. Furthermore, the review includes how a 3DP nasal cast can contribute to the development of nose-to-brain drug delivery along with looking into how bioprinting could be used for regenerating nerves and how 3D-printed drugs could offer practical benefits to patients suffering from neurological diseases via polypill.
引用
收藏
页数:16
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