Can Anti-inflammatory Drugs used in Plastic Surgery Procedures Increase the Risk of Hematoma?

被引：4

作者：

Chen, Zhibing ^{[1
]}

Zhou, Jianwen ^{[2
]}

He, Qiang ^{[1
]}

Feng, Shuang ^{[1
]}

Wa, Qingbiao ^{[1
]}

Chen, Xiaohan ^{[3
]}

机构：

[1] Chengdu Second Peoples Hosp, Dept Ctr Med Cosmetol, Chengdu 610017, Sichuan, Peoples R China

[2] Chengdu Second Peoples Hosp, Dept Cosmet Plast & Burn Surg, Chengdu 610017, Sichuan, Peoples R China

[3] Hosp Univ Elect Sci & Technol China, Dept Geriatr, Sichuan Prov Peoples Hosp, Chengdu 610072, Sichuan, Peoples R China

来源：

AESTHETIC PLASTIC SURGERY | 2023年 / 47卷 / 02期

关键词：

Anti-inflammatory drugs; NSAIDs; Hematoma; Plastic surgery; PRISMA; POSTOPERATIVE PAIN; BLEEDING RISK; BREAST AUGMENTATION; KETOROLAC SAFE; IBUPROFEN; CELECOXIB; TONSILLECTOMY; ACETAMINOPHEN; COMPLICATIONS; METAANALYSIS;

D O I：

10.1007/s00266-022-03194-x

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Background Anti-inflammatory drugs are commonly used to lower inflammation which is linked to a variety of disorders. It acts by inhibiting cyclooxygenase-mediated prostaglandin synthesis at the molecular level. Hematoma is related with the use of anti-inflammatory medications. However, the specific link is still unknown. Thus, the main objective of the study is to find out the association of hematoma with ant-inflammatory drugs. Material and Methods The relevant studies were searched in PubMed and screened based on inclusion and exclusion criteria. The quality of full-text studies was assessed using suitable Newcastle-Ottawa Scale. The overall estimate was calculated in terms of odds ratio with 95% confidence interval. The random effect model was used. The qualitative analysis of publication bias was done through funnel plot. Results The overall estimate measures [OR 1.01 (0.50, 2.06)] have shown non-significant risk of hematoma with use of anti-inflammatory drugs in plastic surgery as compared to non-anti-inflammatory drugs. The heterogeneity among studies was found to be 34%. The subgroup analysis of individual drugs was not done due to availability of a smaller number of studies. Conclusion Based on available data, there is no significant risk of hematoma with use of anti-inflammatory drugs in plastic surgery.

引用

页码：862 / 871

页数：10