Autologous hematopoietic recovery after allogeneic hematopoietic stem cell transplantation: A case-based review

被引:0
|
作者
Shi, Xiumin [1 ]
Liu, Xiaoliang [1 ]
Tang, Yang [1 ]
Tan, Yehui [1 ]
Han, Wei [1 ]
Gao, Sujun [1 ,2 ]
机构
[1] First Hosp Jilin Univ, Dept Hematol, Changchun, Peoples R China
[2] 1 Xinmin St, Changchun 130021, Jilin, Peoples R China
关键词
Autologous hematopoietic recovery; Allo-HSCT; MAC; Incidence; Prognosis; CHRONIC MYELOGENOUS LEUKEMIA; SEVERE APLASTIC-ANEMIA; GRAFT FAILURE; LYMPHOCYTE INFUSION; REMISSION; RECONSTITUTION; CYCLOPHOSPHAMIDE; REJECTION; BMT; SCT;
D O I
10.1016/j.trim.2023.101920
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is widely applied for the treatment of hematologic malignancies, but autologous hematopoietic recovery (AR) after allo-HSCT is rare clinically, especially after myeloablative conditioning (MAC). The mechanism of AR remains unclear so far, but the prognosis for most patients is relatively good. Second transplantation is preferred after disease relapse. Starting from a real-life clinical case scenario, herein we reviewed some of the crucial issues of AR in light of recent refinements, and discussed our patients based on the current evidence.
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页数:5
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