Exploring the Complex Connection Between Diabetes and Cardiovascular Disease: Analyzing Approaches to Mitigate Cardiovascular Risk in Patients With Diabetes

被引:62
作者
Jyotsna, Fnu [1 ]
Ahmed, Areeba [2 ]
Kumar, Kamal [3 ]
Kaur, Paramjeet [4 ]
Chaudhary, Mitul Hareshkumar [5 ]
Kumar, Sagar [3 ]
Khan, Ejaz [6 ]
Khanam, Bushra [7 ]
Shah, Syeda Urooba [8 ]
Varrassi, Giustino [9 ]
Khatri, Mahima [10 ]
Kumar, Satesh [11 ]
Kakadiya, Kishan Ashokbhai [12 ]
机构
[1] Dr B R Ambedkar Med Coll & Hosp, Med, Mohali, India
[2] Fatima Jinnah Med Univ, Med, Lahore, Pakistan
[3] Chandka Med Coll, Med, Larkana, Pakistan
[4] Guru Gobind Singh Med Coll, Internal Med, Faridkot, India
[5] AMA Sch Med, Med, Makati, Philippines
[6] All India Inst Med Sci New Delhi, Dermatol, New Delhi, India
[7] Natl TB Control Ctr, Internal Med, Kathmandu, Nepal
[8] Jinnah Sindh Med Univ, Med, Karachi, Pakistan
[9] Paolo Procacci Fdn, Pain Med, Rome, Italy
[10] Dow Univ Hlth Sci, Med & Surg, Karachi, Pakistan
[11] Shaheed Mohtarma Benazir Bhutto Med Coll, Med & Surg, Karachi, Pakistan
[12] Govt Med Coll, Med, Surat, India
关键词
treatment options; preventive measures; insulin resistance; cardiovascular risk; cardiovascular disease (cvd); diabetes; MANAGEMENT; OUTCOMES; EMPAGLIFLOZIN; HYPERTENSION; NATIONWIDE; MORTALITY;
D O I
10.7759/cureus.43882
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cardiovascular disease (CVD) is the primary cause of morbidity and mortality in individuals diagnosed with diabetes mellitus. This narrative review offers a comprehensive examination of the complex correlation between diabetes and cardiovascular complications. The objective of this review is to analyze the most recent evidence on preventive measures and treatment options for mitigating cardiovascular risk in patients with diabetes, by synthesizing existing literature. Insulin resistance plays a crucial role in connecting diabetes and CVD, leading to the development of dyslipidemia and atherogenesis. As a result, the risk of cardiovascular events in individuals with diabetes is significantly elevated. Moreover, the presence of hyperglycemia-induced oxidative stress and inflammation serves to intensify endothelial dysfunction and vascular damage, thereby exacerbating the risk of cardiovascular complications. The interaction between diabetes and CVD frequently speeds up the development of atherosclerotic plaque, making the plaque more prone to rupture. This can lead to severe cardiovascular events such as myocardial infarction and stroke. It is crucial to comprehend the intricate relationship between diabetes and CVD in order to formulate effective strategies aimed at enhancing patient outcomes and mitigating the burden associated with these interconnected chronic conditions. Healthcare practitioners can enhance the quality of life and reduce mortality rates associated with CVD in diabetic patients by thoroughly examining evidence-based preventive measures and treatment options. This approach allows them to make informed decisions when managing cardiovascular risk. In summary, this narrative review provides a valuable resource for healthcare professionals and researchers, presenting a comprehensive analysis of the complex relationship between diabetes and CVD. By providing a comprehensive analysis of the latest evidence and elucidating the underlying mechanisms, this review seeks to establish a foundation for the development of innovative strategies in diabetes management. These strategies have the potential to significantly improve cardiovascular outcomes and enhance overall patient care.
引用
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页数:15
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