Targeting STAT5B in T-cell acute lymphoblastic leukemia

被引：0

作者：

Veloso, Alexandra ^{[1
,2
]}

Cools, Jan ^{[1
,2
]}

机构：

[1] Katholieke Univ Leuven, Leuven, Belgium

[2] VIB, Leuven, Belgium

来源：

BLOOD | 2023年 / 142卷 / 03期

关键词：

INHIBITION;

D O I：

10.1182/blood.2023020639

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In this issue of Blood, Tremblay et al demonstrate that STAT5B activation drives proliferation, self-renewal, and chemoresistance of leukemia stem cells (LSCs) in an early T-cell precursor acute lymphoblastic leukemia mouse model and explore STAT5B as a direct therapeutic target (see figure).(1)

引用

页码：215 / 217

页数：3

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