Immature Sacrococcygeal Teratoma: A Case Report and Extensive Review of the Literature

被引:5
作者
Varlas, Valentin Nicolae [1 ,2 ]
Clotea, Eliza Maria [2 ]
Varlas, Roxana Georgiana [2 ]
Pop, Anca [1 ,3 ]
Penes, Ovidiu [1 ,4 ]
Cretoiu, Dragos [5 ,6 ]
Dima, Vlad [7 ]
Balanescu, Laura [1 ,8 ]
机构
[1] Carol Davila Univ Med & Pharm, Fac Med, Bucharest 050474, Romania
[2] Filantropia Clin Hosp, Dept Obstet & Gynecol, Bucharest 011132, Romania
[3] Carol Davila Univ Med & Pharm, Dept Clin Lab Food Safety, 6 Traian Vuia St, Bucharest 020945, Romania
[4] Univ Clin Hosp, Carol Davila Univ Med & Pharm, Dept Intens Care, 37 Dionisie Lupu St, Bucharest 020021, Romania
[5] Alessandrescu Rusescu Natl Inst Mother & Child Hlt, Fetal Med Excellence Res Ctr, Bucharest 020395, Romania
[6] Carol Davila Univ Med & Pharm, Dept Genet, 8 Eroii Sanit Blvd, Bucharest 050474, Romania
[7] Filantropia Clin Hosp, Dept Neonatol, Bucharest 011132, Romania
[8] Children Emergency Hosp Grigore Alexandrescu, Dept Pediat Surg, Bucharest 011743, Romania
关键词
sacrococcygeal teratoma; immature histologic type; prenatal diagnosis; therapeutic approach; recurrence; prognostic; STEM-CELL COMPARTMENTS; FETAL WEIGHT RATIO; TUMOR VOLUME; IMMUNOHISTOCHEMICAL LOCALIZATION; PROTOCOLS MAKEI-83/86; 25-YEAR EXPERIENCE; PRENATAL-DIAGNOSIS; ALPHA-FETOPROTEIN; CHILDREN; MANAGEMENT;
D O I
10.3390/diagnostics14030246
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Immature sacrococcygeal teratoma represents a histological form with rapid tumor growth, a risk of premature birth, an enhanced rate of complications, an increased risk of recurrence, and a higher mortality rate than the mature type. Thus, prenatal diagnosis of immature forms would significantly improve the prognosis of these cases. To this end, we performed an extensive literature review on the diagnosis, therapeutic management, and follow-up of immature teratomas. Regarding this medical conduct, we also presented our case. In conclusion, the early identification of immature sacrococcygeal teratomas with or without other associated structural abnormalities and their correct therapeutic approach are basic principles for a favorable evolution of these cases.
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页数:16
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