Insights from a retrospective study: an understanding of pediatric colorectal carcinoma

被引:2
|
作者
Guzman, Sofia Brenes [1 ]
Garcia, Edgar Fernando Oliver [1 ]
Rojas, Edgar Guillermo Lazcano [2 ]
Tinajero, Alfa Guadalupe Barraza [1 ]
Meza, Daniela Hernandez [1 ]
Chavez, Jose Luis Gonzalez [2 ]
Camacho, Edgar Melo [2 ]
Enriquez, Juan Carlos Nunez [1 ,2 ]
机构
[1] Pediat Hosp Natl Med Ctr Siglo XXI, Mexican Social Secur Inst, Dept Pediat High Specialty Surg, Ignacio Morones Prieto St 605, Mexico City 06720, Mexico
[2] Inst Social Secur & Serv State Workers, Natl Med Ctr Noviembre 20, Dept Pediat Surg, Mexico City, Mexico
关键词
Colorectal carcinoma; Pediatric colorectal carcinoma; Atypical presentation; Pediatric colorectal carcinoma prognosis; CHILDREN; CANCER; MANAGEMENT; FEATURES;
D O I
10.1186/s43054-024-00246-6
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Pediatric colorectal cancer, comprising just 1% of childhood cancers, has surged among young individuals, underscoring its significant health impact. Diagnostic challenges arise from atypical presentation and nonspecific symptoms in 90% of cases, leading to delayed detection in 19%.Methods A 2-year retrospective study of pediatric colorectal carcinoma cases was conducted across a specialized surgical pediatric center. Data were gathered, including age, symptoms, diagnostics, treatments, and outcomes.Results Six colorectal carcinoma cases (median age, 16) were documented, mainly in males (66%). Predominant histological types included mucinous adenocarcinoma and signet ring cell carcinoma. Metastasis was present in all cases, with symptoms including hematochezia (83%), abdominal pain (100%), weight loss (66%), and anemia (100%). Diagnosis often faced misidentification, fostering disease progression and metastasis. Various diagnostic and treatment modalities were employed, including surgery and neo-adjuvant or adjuvant chemotherapy.Conclusion Swift detection and intervention for pediatric colorectal carcinoma are pivotal. Efficient diagnostics and heightened awareness among medical professionals and the public are imperative. Early surgical intervention remains a cornerstone, especially for patients with pertinent family histories and characteristic symptoms. Tailored guidelines for pediatric patients are needed to enhance outcomes and survival. center dot CC is rare but increasing among young individuals.center dot CC is often diagnosed late or misdiagnosed due to atypical presentation and nonspecific symptoms.center dot Early detection and treatment of CC are crucial for patient survival.center dot CC treatment involves surgery, chemotherapy, and targeted therapies.center dot Awareness of CC symptoms and risk factors is vital for early detection and management.
引用
收藏
页数:8
相关论文
共 50 条
  • [41] Restratification of intermediate risk factors on the recurrence of papillary thyroid carcinoma: a retrospective cohort study
    Chen, Qiang
    Zou, Xiuhe
    Liu, Feng
    Su, Anping
    Jiang, Yong
    Wei, Tao
    Gong, Rixiang
    Zhu, Jingqiang
    Li, Zhihui
    INTERNATIONAL JOURNAL OF SURGERY, 2025, 111 (01) : 884 - 890
  • [42] A study of BRAF mutation in colorectal carcinoma in Indian population
    Saxena, Shilpi
    Srinivas, V.
    Deb, Prabal
    Raman, Deep Kumar
    Jagani, Rajat
    JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, 2018, 14 (06) : 1403 - 1406
  • [43] Deficient mismatch repair and RAS mutation in colorectal carcinoma patients: a retrospective study in Eastern China
    Zhang, Xiangyan
    Ran, Wenwen
    Wu, Jie
    Li, Hong
    Liu, Huamin
    Wang, Lili
    Xiao, Yujing
    Wang, Xiaonan
    Li, Yujun
    Xing, Xiaoming
    PEERJ, 2018, 6
  • [44] Clinical outcomes of endoscopic submucosal dissection for large pedunculated colorectal carcinoma: A retrospective multicenter study
    Inagaki, Katsuaki
    Yamashita, Ken
    Oka, Shiro
    Tanino, Fumiaki
    Yamamoto, Noriko
    Kamigaichi, Yuki
    Tamari, Hirosato
    Nishimura, Tomoyuki
    Okamoto, Yuki
    Tanaka, Hidenori
    Kotachi, Takahiro
    Yuge, Ryo
    Urabe, Yuji
    Kitadai, Yasuhiko
    Tanaka, Shinji
    DEN OPEN, 2024, 4 (01):
  • [45] Phacoemulsification with Intraocular Lens Implantation in Pediatric Uveitis: A Retrospective Study
    Ganesh, Sudha K.
    Mistry, Saurabh
    OCULAR IMMUNOLOGY AND INFLAMMATION, 2018, 26 (02) : 305 - 312
  • [46] Neutrophilic Myocarditis: Insights from a Forensic Centre's Retrospective Study
    Neagu, Oana
    Luca, Lacramioara
    Bosa, Maria
    Tita, Alina
    Ceausu, Mihail Constantin
    DIAGNOSTICS, 2024, 14 (14)
  • [47] Evaluating Lichen Sclerosus in Phimosis: Insights From a Multidisciplinary Retrospective Study
    Bighetti, Stefano
    Mancon, Stefano
    Suardi, Nazareno
    Calzavara-Pinton, Piergiacomo
    Maione, Vincenzo
    Arisi, Mariachiara
    Lughezzani, Giovanni
    Zerbinati, Nicola
    Ghini, Iacopo
    Bettolini, Luca
    AUSTRALASIAN JOURNAL OF DERMATOLOGY, 2025, : e39 - e42
  • [48] Surgery for recurrent adrenocortical carcinoma: A multicenter retrospective study
    Simon, Guenole
    Pattou, Francois
    Mirallie, Eric
    Lifante, Jean Christophe
    Nomine, Claire
    Arnault, Vincent
    de Calan, Loic
    Gaillard, Cecile
    Carnaille, Bruno
    Brunaud, Laurent
    Laplace, Nathalie
    Caiazzo, Robert
    Blanchard, Claire
    SURGERY, 2017, 161 (01) : 249 - 255
  • [49] Thoracoscopic esophagomyotomy for achalasia in the pediatric population: A retrospective cohort study
    Duggan, Eileen M.
    Nurko, Samuel
    Smithers, Charles J.
    Rodriguez, Leonel
    Fox, Victor L.
    Fishman, Steven J.
    JOURNAL OF PEDIATRIC SURGERY, 2019, 54 (03) : 572 - 576
  • [50] Understanding Ectopic Kidneys: Insights from a Single-Center Study
    Koksoy, Adem Yasin
    Bako, Derya
    Sahin, Mustafa Kursat
    GUNCEL PEDIATRI-JOURNAL OF CURRENT PEDIATRICS, 2024, 22 (03): : 150 - 157