Can computer alerts in general practitioners' software upgrade cancer screening participation? A monocentric randomized study in France

Colorectal cancer is the third most common cancer in France, and the second regarding mortality with almost 17,100 deaths each year. When screened at an early stage, the five-year survival is around 90 %. Since 2008, a screening program has been introduced in France with the fecal occult blood test. Ten years later, the targeted participation for the screening program is at least 45 % when the actual French average participation is around 30,2 %. We tried to find an efficient way to help general practitioners to recognise patients that did not do the test with a pop-up alert in their informatics files. We built our prospective study in a health center in Val d'Oise (France). We randomized 2230 patients in two equal groups, one control at one with the alert in files. We controlled the patients' status each month for 6 months. At the end of study, 152 (13,6 %) patients did the test in the control group and 179 (16 %) in the intervention group. In intention to treat, we found no difference between the two groups (P = 0.11). Multivariate analysis proved that consulting their general practitioner enhanced participation (P = 0.02). We showed the positive influence of a consultation with the general practitioner who can improve participation for this screening program. Our study was certainly too short in time and with a too small sample to prove a significant difference, and more investigation could confirm our hypothesis.