Recent findings on drug hypersensitivity in children

被引:1
|
作者
Felix, Mara Morelo Rocha [1 ]
Kuschnir, Fabio Chigres [2 ]
Boechat, Jose Laerte [3 ,4 ]
Castells, Mariana [5 ]
机构
[1] Univ Fed Estado Rio De Janeiro, Sch Med & Surg, Dept Gen Med, Rio De Janeiro, Brazil
[2] Univ Estado Rio De Janeiro, Fac Med, Dept Pediat, Rio De Janeiro, Brazil
[3] Univ Fed Fluminense, Fac Med, Internal Med Dept, Clin Immunol Serv, Niteroi, Brazil
[4] Univ Porto, Fac Med, Dept Pathol, Basic & Clin Immunol Unit, Porto, Portugal
[5] Brigham & Womens Hosp, Dept Med, Div Rheumatol Allergy & Immunol, Boston, MA USA
来源
FRONTIERS IN ALLERGY | 2024年 / 5卷
关键词
drug hypersensitivity; children; allergy; antibiotic; vaccines; severe cutaneous adverse drug reactions; Stevens-Johnson syndrome; toxic epidermal necrolysis; STEVENS-JOHNSON SYNDROME; TOXIC EPIDERMAL NECROLYSIS; SYSTEMIC SYMPTOMS DRESS; HOSPITALIZED-PATIENTS; ERYTHEMA MULTIFORME; PENICILLIN ALLERGY; ASSOCIATION; EOSINOPHILIA;
D O I
10.3389/falgy.2024.1330517
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Drug hypersensitivity reactions (DHR) in children have a significant impact on clinical practice and public health. Both under-diagnosis (due to under-reporting) and over-diagnosis (due to the overuse of the term "allergy") are potential issues. The aim of this narrative review is to describe the most recent findings of DHR in children/adolescents and gaps regarding epidemiology, antibiotic allergy, antiepileptic hypersensitivity, vaccine allergy, and severe cutaneous adverse reactions (SCAR) in this age group.
引用
收藏
页数:7
相关论文
共 50 条
  • [41] Non-IgE-mediated drug-induced hypersensitivity reactions in pediatrics
    Chow, Timothy G.
    Muzaffar, Anum F.
    Alvarez-Arango, Santiago
    CURRENT OPINION IN PEDIATRICS, 2024, 36 (06) : 674 - 683
  • [42] Delayed Drug Hypersensitivity Reactions: Molecular Recognition, Genetic Susceptibility, and Immune Mediators
    Chu, Mu-Tzu
    Chang, Wan-Chun
    Pao, Shih-Cheng
    Hung, Shuen-Iu
    BIOMEDICINES, 2023, 11 (01)
  • [43] Hypersensitivity reactions to non-betalactam antibiotics in children: An extensive review
    Kuyucu, Semanur
    Mori, Francesca
    Atanaskovic-Markovic, Marina
    Caubet, Jean-Christoph
    Terreehorst, Ingrid
    Gomes, Eva
    Brockow, Knut
    PEDIATRIC ALLERGY AND IMMUNOLOGY, 2014, 25 (06) : 534 - 543
  • [44] Drug Hypersensitivity Reactions: Pathomechanism and Clinical Symptoms
    Pichler, Werner J.
    Adam, Jaqueline
    Daubner, Barbara
    Gentinetta, Thomas
    Keller, Monika
    Yerly, Daniel
    MEDICAL CLINICS OF NORTH AMERICA, 2010, 94 (04) : 645 - +
  • [45] Update on the Genetic Basis of Drug Hypersensitivity Reactions
    Jurado-Escobar, R.
    Perkins, J. R.
    Garcia-Martin, E.
    Isidoro-Garcia, M.
    Dona, I
    Torres, M. J.
    Cornejo-Garcia, J. A.
    JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY, 2017, 27 (06) : 336 - 345
  • [46] Evaluation of the Drug Hypersensitivity Reactions Prevalence in Hospitalized Children in Sari City from 2014 to 2018: An Original Research
    Houshmand, Hamidreza
    Shiran, Mohammad Reza
    Ghaffari, Javad
    Abounoori, Mahdi
    Maddah, Mohammad Moein
    Razavi, Alireza
    Askari, Sajjad
    Bayat, Sara
    Houshmand, Gholamreza
    JOURNAL OF PEDIATRICS REVIEW, 2021, 9 (03) : 229 - 238
  • [47] Pharmacogenetics of drug hypersensitivity
    Philips, Elizabeth J.
    Mallal, Simon A.
    PHARMACOGENOMICS, 2010, 11 (07) : 973 - 987
  • [48] Hypersensitivity drug reactions
    Thong, Bernard Y.
    Blanca, Miguel
    CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 14 (04) : 269 - 270
  • [49] Immediate Drug Hypersensitivity
    Wickner, Paige G.
    Hong, David
    CURRENT ALLERGY AND ASTHMA REPORTS, 2016, 16 (07)
  • [50] Model Based Evaluation of Hypersensitivity Adverse Drug Reactions to Antimicrobial Agents in Children
    Elzagallaai, Abdelbaset A.
    Rieder, Michael J.
    FRONTIERS IN PHARMACOLOGY, 2021, 12