Spinal Cord Infarction in an Adolescent with Protein S Deficiency: A Case Report and Literature Review

被引：0
作者：
Kubota, Takafumi
Hosaka, Tatsuhiko
Ando, Daisuke
Ikeda, Kensuke [1 ]
Izumi, Rumiko
Misu, Tatsuro
Warita, Hitoshi
Aoki, Masashi
机构：
[1] Tohoku Univ Hosp, Dept Neurol, Sendai, Japan
来源：
INTERNAL MEDICINE | 2023年 / 62卷 / 16期
关键词：
spinal cord infarction; stroke; thrombosis; thrombotic disorder; protein S deficiency; anticoagulation; ISCHEMIC-STROKE; ARTERY SYNDROME; CHILDREN; ONSET;
D O I：
10.2169/internalmedicine.0153-22
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Protein S deficiency causes spinal cord infarction in rare cases. We herein report the first case of severe cervicothoracic cord infarction in an adolescent with protein S deficiency. A 16-year-old boy presented with neck pain, four-limb paralysis, and numbness. Magnetic resonance imaging revealed spinal artery infarction in the C4 to Th4 area. Protein S antigen and activity were decreased. The patient was diagnosed with protein S deficiency-associated cervicothoracic cord infarction, which was treated with anticoagulation. Protein S deficiency should be considered as a potential cause of spinal cord infarction in young healthy patients and should be appropriately treated with anticoagulation.
引用
收藏
页码：2415 / 2418
页数：4
相关论文
共 50 条
[21]   Spinal Cord Ischemia Related to Disc Herniation: Case Report and a Review of the Literature [J].
Aalbers, Marlien W. ;
Groen, Rob J. M. ;
Appelman, Auke P. A. ;
Heersema, Thea D. J. ;
Wokke, Beatrijs H. A. ;
Oterdoom, D. L. Marinus .
INTERNATIONAL MEDICAL CASE REPORTS JOURNAL, 2021, 14 :429-433
[22]   NifedipineFirst report of spinal cord infarction in an elderly patient: case report [J].
Reactions Weekly, 2006, 1087 (1) :22-22
[23]   Purely intramedullary spinal cord primitive neuroectodermal tumor: case report and review of the literature [J].
Otero-Rodriguez, A. ;
Hinojosa, J. ;
Esparza, J. ;
Munoz, M. J. ;
Iglesias, S. ;
Rodriguez-Gil, Y. ;
Ricoy, J. R. .
NEUROCIRUGIA, 2009, 20 (04) :381-386
[24]   An aggressive parameningeal rhabdomyosarcoma with multiple spinal cord metastases: a case report and review of the literature [J].
Yavas, Guler ;
Karabagli, Pinar ;
Paksoy, Yahya ;
Yavas, Cagdas ;
Karabagli, Hakan ;
Koksal, Yavuz .
CHILDS NERVOUS SYSTEM, 2017, 33 (05) :843-847
[25]   Spinal cord ganglioglioma in a child with neurofibromatosis Type 2 - Case report and literature review [J].
Sawin, PD ;
Theodore, N ;
Rekate, HL .
JOURNAL OF NEUROSURGERY, 1999, 90 (04) :231-233
[26]   Spinal Cord Injury without Radiographic Abnormality (SCIWORA): a case report and literature review [J].
Morelli, Nicola ;
Poggiali, Erika ;
Ioannilli, Eva ;
De Mitri, Paola ;
Corvi, Andrea ;
Cervellin, Gianfranco ;
Vercelli, Andrea .
EMERGENCY CARE JOURNAL, 2023, 19 (02)
[27]   Apixaban Use in Patients with Protein C and S Deficiency: A Case Series and Review of Literature [J].
Al Sulaiman, Khalid ;
Alsuwayyid, Faisal ;
Alrashidi, Abdulrahman ;
Alhijris, Mohammed ;
Almutairi, Faisal ;
Alharthi, Fahad ;
Abu Esba, Laila Carolina ;
Aljuhani, Ohoud ;
Badreldin, Hisham A. .
JOURNAL OF BLOOD MEDICINE, 2022, 13 :105-111
[28]   Spontaneous spinal cord infarction: a systematic review [J].
Gharios, Maria ;
Stenimahitis, Vasilios ;
El-Hajj, Victor Gabriel ;
Mahdi, Omar Ali ;
Fletcher-Sandersjoo, Alexander ;
Jabbour, Pascal ;
Andersson, Magnus ;
Hultling, Claes ;
Elmi-Terander, Adrian ;
Edstrom, Erik .
BMJ NEUROLOGY OPEN, 2024, 6 (01)
[29]   Spinal cord infarction during use of zolmitriptan: A case report [J].
Vijayan, N ;
Peacock, JH .
HEADACHE, 2000, 40 (01) :57-60
[30]   Isolated gastric varices associated with antiphospholipid syndrome and protein S deficiency: a case report and review of the literature [J].
Li, Xueyan ;
Wu, Jiandi ;
Fang, Feifei ;
Liu, Ying ;
Jiang, Wewei ;
Li, Gangping ;
Song, Jun .
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2024, 52 (04)
12345